Protein Alignment Nep3 and nep-11

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 797
• Identity: 261/797 - (32%)
• Similarity: 425/797 - (53%)
• Gaps: 65/797 - (8%)

  Fly    42 WNWRSRNKTEKWLL-ITTFVMAITIFTLLIVLFTD----------------GGSSDATKH----- 84
            | |:||...||.|| :......:|...|.:::.||                .|..|.|::
 Worm    65 W-WKSRTTMEKLLLPVLLLFCLLTAVLLAVIINTDKRIEAMKTDHATQTEHAGFGDPTENPTKTA 128

  Fly    85 ----VLHVQPHQKDCP-----SGNELP-----CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCN 135
                |..:.|.....|     :..|.|     |....|:.|::..|.:::.:|||||||:.::|.
 Worm   129 EDPRVPPIVPEAPTSPEPEVTTSTEKPKEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACG 193

  Fly   136 QWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKL 200
            ||...:|||:....:|||....:..:..:|.:||:...: :|::...|:..|.||::..: :::|
 Worm   194 QWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVT-ESESINMARATYRSCMNKTQ-LDEL 256

  Fly   201 GAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQID 265
            ...|:.:.|.::|.|.:.:..::...:.....|......|..:..|...|..|.||:||:.:.||
 Worm   257 MTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFID 321

  Fly   266 QGGLTL--PTADYYNNKT--DNHRKVLNEYIEYMTKVCVLLGA------NESDARAQMIGVINFE 320
            |..|.|  .|.|||.|.|  .:|   :..|.:|:.::..||..      :||:..|.:..:|:||
 Worm   322 QSTLALGRGTRDYYLNTTLFSSH---MTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFE 383

  Fly   321 KKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDN-AMQMVGRRVTDDEVVVVYAPD 384
            .:||.|.:..::|||...:|:..|::.|..|.|.::|...|.: |...:.....::..:::...:
 Worm   384 IELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLTHLFHNETEIIICEIE 448

  Fly   385 FLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRY 449
            :|:::|::|   |:|:.|.:|  ||::|:.|::....|.:.|.|..:...|.:.|.......|:.
 Worm   449 YLQHVSELI---EKTDVGLLT--NYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKD 508

  Fly   450 CVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQ 514
            |....:.|:..|.|||:|:..|....|..|.:||..:|.:|...::...|:|::|:..||||||.
 Worm   509 CAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANS 573

  Fly   515 ISDMIGFPDYILDPVELDKKYAELNIT-PNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQ 578
            :.:.||:||...|..:|||:|..|:|: .:.|:....:..::......::|.:|.:|..:.::|.
 Worm   574 MINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPA 638

  Fly   579 TVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINR 643
            .|||:|:|.||.|.|||||||.|||....||::|:||:|.|:|||:||.|||||.:|||.||::.
 Worm   639 VVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHN 703

  Fly   644 WWDSKSIERFNEKSECIARQYSGY---KMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRD 705
            ||...|:..|:.:..||..||..|   |.|.| :|||.|.|||||||||:|.|:.|||:..::..
 Worm   704 WWSESSLNSFDTRRRCIVEQYGNYTVPKTNFR-VNGKLTQGENIADNGGVKEAFQAYQKYVTENG 767

  Fly   706 VDILKLPGL-NLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVF 769
            .: .:|||| ..|:.|:||||:|..||....:...:.|:..|.|||..|||||.||||:.||:|:
 Worm   768 EE-PRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVY 831

  Fly   770 QCKPGKRMNPTEKCEVW 786
            :|.....:||..||.||
 Worm   832 KCPRNAPVNPDHKCIVW 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	234/676 (35%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	233/675 (35%)