Protein Alignment Nep3 and nep-10

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 807
• Identity: 169/807 - (20%)
• Similarity: 316/807 - (39%)
• Gaps: 191/807 - (23%)

  Fly    54 LLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELP--------CLNKHCIF 110
            ||:..|:..:|:...:.:.......||  ..:....|.||.....:|..        |.:..||.
 Worm    22 LLLIVFLALVTVHIKMTIDVAPVFKSD--DPLPRGDPDQKPATIDSETQTVDEPRNVCESPECIT 84

  Fly   111 ASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGK--STWGTFGKLEQMNQLIIRNVLEKPAK 173
            .:.|:....|.:||||.|||.:.|.::.:::.|.:|:  :...|..||  :.:.:::|      |
 Worm    85 LAHELHNYKDPSVDPCQDFYQHFCGKFYEHSAIGQGRMATKRSTLSKL--IREFLLKN------K 141

  Fly   174 SFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLL------LQIGGWNVTKSGYNVANWTMGHT 232
            :..|.:|...|..|..|.:. :.:..|.:.|...||      .:||.|.|....::.:.:.:...
 Worm   142 TSTSKSENTMKQVYAKCREL-QKISDLNSIPPQALLDIFSDIKKIGAWPVLDKDWDGSKFNLNEM 205

  Fly   233 LKILHNK-------YNFN------CLFGWAIGEDDKNS----------SRHVIQIDQGGLTLPTA 274
            |:.|.|.       ::|:      .|....:.:..:.|          ..:.|::|||
 Worm   206 LRQLVNLGETHLGFFHFDFIARPYVLIKPPLKQGVQKSVLEKVVKMILEANEIKMDQG------- 263

  Fly   275 DYYNNKTDNHRKVLNEYIEYMTKVCV---------LLGANESDARAQMIGVINFEKKLANITIPL 330
                     ..:.|:||.|...::.:         ::|......|....|:|
 Worm   264 ---------FSEDLDEYFELSNRIKIDKLPRTSRSIVGLLPDVRRINFRGLI------------- 306

  Fly   331 EDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLK----NLSD 391
                        :::...||:..||.               ....:||..:.|.|::    |..|
 Worm   307 ------------LEMMPRSKMNRFLG---------------TLFQKVVTYHHPLFVRDNETNHLD 344

  Fly   392 IILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEI--------WR 448
            .|::.....    .|.|||::..:.:....|:...:...:...|.::     :|:        .|
 Worm   345 TIIRSTSNR----ALANYLIFNFIHSSIKFLTFGLKSDRERCEKIVV-----QELPRPSLRVFMR 400

  Fly   449 YCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMN-LQNLTWVDKQT---REKAI 509
            .||...|                        .:.:|::.|..|.| |:.:...|..|   :::.:
 Worm   401 NCVDKGN------------------------REEVAKLTETVKENVLEMIRESDSFTPSVKKRVL 441

  Fly   510 EKANQISDMIGFPDYILDPVELDKKYAELNI-TPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNW 573
            :|...|..:||:||:...|..|||:|..|.: ..::|::.:.::....|:..::.|.
 Worm   442 KKVEAIGAIIGYPDHFDPPGTLDKEYENLTLDASDSYYKMSQKLHQLRLQHQMEFLA-------- 498

  Fly   574 GMTPQT-------VNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQ 631
            |.||.:       |||:|....|.:...|..|..||||...|:.:|....|.::|||..|:.|
 Worm   499 GQTPLSPSDQVLEVNAHYDSKDNALTVLAPFLDDPFFDSTYPEYVNLIFTGFLIGHEFGHSID-- 561

  Fly   632 GREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY--KMNGRTLNGKQTLGENIADNGGLKAAY 694
                .|....:.|:.::.:..:.::::|:..||..|  ..:|:.:||...:||.:.|..|....:
 Worm   562 ----PKILRRDGWYKTEDMTEYGKRAQCLIDQYDNYDDPDHGKQMNGTYCIGEIVGDWVGRDVTW 622

  Fly   695 HAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTL 759
            .|:::....:...::.....||  .||:|...:..:|...:.: :|.|:..|||....|||.|..
 Worm   623 RAFKKMDLSKMQKLIGFEDKNL--DQLYFRIQSLFFCGPRSMK-SLEQLLSDPHPTEVFRVNGIY 684

  Fly   760 SNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            |||.:||:.|.|..|..|||.:||:::
 Worm   685 SNMPQFAKAFNCPIGSPMNPEKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	153/726 (21%)
nep-10	NP_494532.2	M13	97..709	CDD:341056	153/726 (21%)