Protein Alignment Nep3 and nep-13

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 747
• Identity: 169/747 - (22%)
• Similarity: 311/747 - (41%)
• Gaps: 161/747 - (21%)

  Fly   103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEG-----KSTWGTFGKLEQMNQL 162
            |....||..||.:|...:..:|||:|||.|||.:: :.:.:.:|     |.|.    .::.:.|.
 Worm    84 CKTAECITLSSTLLNWQNTNIDPCEDFYEYSCGRY-QEHTLNDGIRANEKDTI----VMKLIRQF 143

  Fly   163 IIRNVLEKPAKSFKSDAERKAKVYYESC----LDADEHME-KLGAKPMNDLLLQIGGWNVTKSGY 222
            :::|      :|..|::|....:.||.|    ...:.|.| ::..:.:.:.:.:||.|.:....:
 Worm   144 VLKN------QSTTSNSENALMLLYEKCSLRYRMENRHQETEVIQREVFENIRKIGSWPIADKNW 202

  Fly   223 NVANWTMGHTLKILHNKYNFNCL-FGWAIGEDDKNSSRHVIQIDQGGLTL------PTADYYNNK 280
            |.:::.:.:   :|.|..:.:.| ||.        ....||::.....|.      ||...::..
 Worm   203 NSSHFNLNN---MLSNMASIHMLPFGL--------FETRVIELYPMNTTAKQLVIRPTKLKFSIP 256

  Fly   281 TDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQL 345
            .:...:.:.:.:.......::....|..|.:     ...:|::.||.|..:.:        |..|
 Worm   257 QEELVRAIRDLLSVNGITSIMKKVKEDVAES-----FALDKEIGNIHIDPQPK--------PATL 308

  Fly   346 RQLSKLAPFL---------------NW----TDHFDNAMQM-VGRRVTDDEVVVVYAPDFLKNLS 390
            .:|.|..|.:               ||    |..|....:: .|:.               .|||
 Worm   309 SELQKAVPDIDFERIIKSYLNPKTGNWSSLRTKIFSARFELFFGKN---------------NNLS 358

  Fly   391 DIILKMEQTEEGKITLNNYLVWQAVRTLTSCL---SKPFRDAYKGVRKALMGSDGGEEIWRYCVS 452
            .||.:.:..     .|.|||..:.:.......   :|.|.|           .|       :|..
 Worm   359 SIIARTKPR-----ILANYLFLKYIEYAYFFFFDNTKVFSD-----------DD-------FCTE 400

  Fly   453 DTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISD 517
            .....:..|...:|||..|..|:...|.:::..::.|:...:.|.||:...|||.||||..::..
 Worm   401 VVTTSLPRASLRVFVRNHFKKENMAVASEIVEVVKTAYVEIINNSTWLHNSTRESAIEKVVKMKK 465

  Fly   518 MIGFPDYILDPVELDKKYAELNIT-PNAYFENNIQVAIYNLKSNLKRLDQPVN--KTNWGMTP-- 577
            :||:.:.......||:.:..|.:: .:::|       :...|.|..:::|.::  .::..:.|
 Worm   466 VIGYTEEYERTGALDEMFETLQLSRSDSFF-------VLMTKVNRFKIEQLMDFVSSDSLLNPIE 523

  Fly   578 --QTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGN 640
              ...||:|.||||.:......|..|.||...|:.:....:|.|:.||:.||||..||:.|:.|.
 Worm   524 PLVMANAFYFPTKNLLNVLVPFLDKPLFDFKYPRYVAMAGVGRVLAHEIGHAFDINGRQTDEIGR 588

  Fly   641 INRWWDSKSIERFNEKSECIARQYSGYK---MNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKS 702
            ...||..:..|.::.:|||.|.|::.:|   ..|:. ||.:.|.|.|||..|::|::.|:::
 Worm   589 TRDWWTREDTEEYDRRSECFAEQFTNFKDPSFKGKQ-NGTEVLAEIIADALGMEASWIAFKK--- 649

  Fly   703 DRDVDILKLPGLNLTHSQ------------LFFVSFAQVWCS-STTDETNLLQMEKDPHSPSQFR 754
                       :|||..|            |:|...|..:|: |..:|....|:.   |..::||
 Worm   650 -----------INLTEEQGLIQFEDHDFGKLYFQVAALDFCAPSRIEERYSDQLS---HPTNKFR 700

  Fly   755 VIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            :.|..||.:.||:.::|..|.:|||.::|:::
 Worm   701 INGAFSNSRAFADTYKCPVGSKMNPVQRCDMF 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	162/723 (22%)
nep-13	NP_001342017.1	M13	104..729	CDD:341056	162/722 (22%)