Protein Alignment Nep3 and Nep2

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_061497288.1
• Gene: Nep2 / 1281326
• VectorBaseID: AGAMI1_002834
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 789
• Identity: 279/789 - (35%)
• Similarity: 443/789 - (56%)
• Gaps: 58/789 - (7%)

  Fly    34 RYHTARATWNWRSRNKTEKWLLITTFVMAITIFTLLIVLFT---------DGGSSDATK------ 83
            |:.....:| ||.|...||.|.:.:.|..:.:..|:|.|.|         :..||.|..
Mosquito    26 RFSGKNPSW-WRRRTALEKVLTLISVVCGVAVVALIISLLTVVLTDRIQSESSSSSAQPLTAGRR 89

  Fly    84 -HVLHVQPHQ-KDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEG 146
             ..|:..|:. .|.....|..||...||.::|:.|:.:|..|:||||||.|:|.:::|...||:.
Mosquito    90 GKALNKHPNTVVDSGKSAENICLTPGCIHSASKALEQMDQEVEPCDDFYNYACGKFVKETVIPDE 154

  Fly   147 KSTWGTFGKL-----EQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMN 206
            |.:..||..:     :|:..|:...:.:..|..||     .||..|:.|:: ...:|:.|.||:.
Mosquito   155 KVSVNTFSVIGDRLQQQLRSLVSEEISDSEATPFK-----LAKNLYKLCMN-KTRIEEKGIKPLL 213

  Fly   207 DLLLQIGGWNVTK-SGYNV-ANWTMGHTLK-ILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGG 268
            |:...:|||.|.| ..::: ::|:...::| ..:|.|:.:..|.::||.|.|||:|.:|..||..
Mosquito   214 DIHEVLGGWPVLKGDSWDLDSSWSWVKSVKDFRNNGYSTDYFFDFSIGSDLKNSTRRIIDTDQAS 278

  Fly   269 LTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDR 333
            |.: :.:|.....:|  .:::.|..||..:.|||||:|..|:.:::..:|||..||||::|.|.|
Mosquito   279 LGI-SREYLVKGMEN--PIVSAYYNYMVDMAVLLGADEERAKRELLDSLNFEMALANISLPNEKR 340

  Fly   334 RNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQ 398
            ||..|:|:||.:::..:..|:.:|.::|:..::..|..:.::||::|..|.|::.|..:   ::.
Mosquito   341 RNATALYNPMTVKEFQQRYPYTDWLEYFNAILKDTGIVIGEEEVIIVSVPTFMEQLGPL---LQN 402

  Fly   399 TEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVG 463
            |.  |..:.||::|:.....:..|::..|........||.|....|..|:.||..|:..:..:||
Mosquito   403 TP--KRVMANYVMWRISGFSSFFLTEKLRKRQLQYSTALSGKQEQEPRWKECVDITSGSLPISVG 465

  Fly   464 AIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDP 528
            |:::|:.|..:||.||..|:.:|:..|...|:.:.|:|:.||..|:||.:.::..||:||.::|.
Mosquito   466 ALYIRKYFREDSKRAALDMVNDIKSVFVDILKKVDWMDEVTRVSALEKVSTMATHIGYPDELMDD 530

  Fly   529 VELDKKYAELNITPNAYFENNIQVAIYNLK----SNLKRLDQPVNKTNW--GMTPQTVNAYYTPT 587
            .::.:.|.:|...|::.:.|.|   :|..|    ...|:|...||||:|  ...|..|||:|:..
Mosquito   531 AKIAEYYKDLEFQPDSTYLNTI---LYMNKFGTTKAFKKLRIAVNKTDWITHSRPAIVNAFYSSI 592

  Fly   588 KNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIER 652
            :|.|.|||||||..||..:.||.:|:||:|.|:|||:||.||||||::||.||:..||.|.:...
Mosquito   593 ENSIQFPAGILQGQFFSYDRPKYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDWWQSDTKTA 657

  Fly   653 FNEKSECIARQYSGY-----KMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLP 712
            :.||:.||..||..|     |:|   |||..|.|||||||||:|.||:||:|. ::::....:||
Mosquito   658 YLEKARCIIEQYGNYTEPNVKLN---LNGINTQGENIADNGGIKEAYYAYRRW-TEKNGPEQRLP 718

  Fly   713 GLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRM 777
            ||||:..|:|::|.||.|||....||..:::....|||.||||:|.:|||.|||:.|.|..|..|
Mosquito   719 GLNLSPEQMFWLSAAQTWCSVYRPETMKMRITTGVHSPGQFRVLGPMSNMHEFAKDFNCPVGSPM 783

  Fly   778 NPTEKCEVW 786
            ||..|||||
Mosquito   784 NPEHKCEVW 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	248/679 (37%)
Nep2	XP_061497288.1	None