Protein Alignment Nep3 and Nep1

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_553645.4
• Gene: Nep1 / 1279203
• VectorBaseID: AGAMI1_011171
• Length: 869
• Species: Anopheles gambiae
• Alignment Length: 745
• Identity: 281/745 - (37%)
• Similarity: 428/745 - (57%)
• Gaps: 34/745 - (4%)

  Fly    57 TTFVMAITIFTLLIVLF-----TDGGSSDATKHVLHVQPHQKDCP--------SGNELPCLNKHC 108
            |..::.|.:..||:.|.     .||.|.      ....|....||        |.|  .||...|
Mosquito   144 TMLLVGIALGILLVYLVGRYRQLDGKSG------CSADPFAPGCPDVTDESRRSSN--ICLTDEC 200

  Fly   109 IFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAK 173
            :..:|.:|.::|.|.|||.||:.::|..|.|.:.|||.:|:..||..|....|.|::.|||:|..
Mosquito   201 VRTASSLLAAMDRTADPCKDFFQFACGTWNKMHVIPEDRSSISTFEVLADQQQAILKGVLEEPVN 265

  Fly   174 SFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHN 238
            ...:.|.:|||.:|:||::. |.:..|..:.:...|.::|||.|.:..:.|.:.::.|.|..|..
Mosquito   266 KEDNRATKKAKAFYKSCMNL-EQIRLLDVQALRKSLKKLGGWPVIEKNWTVPSTSIEHLLGKLTG 329

  Fly   239 KYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLG 303
            :|:...|....:|.||||||.::||:||..|.||:.|||..::....  :..|..|||::.:|:|
Mosquito   330 EYDEPGLVELYVGADDKNSSMNIIQVDQLLLALPSRDYYLKESSEGD--MKAYHRYMTQIAILMG 392

  Fly   304 ANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMV 368
            |::..|..::..::.||.:|||.|:|..||.:..|:|..:.|.:|.:..|.:||.::....:..|
Mosquito   393 ADKDKAAEELQRIVEFEVRLANATLPEADRHDTSAIYTKITLPELQRRVPQINWKEYLQTTLGTV 457

  Fly   369 GRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGV 433
            .  :..:|.:|.||..:|..|..|:     .:..:..::||.:|:.|.::.:.:...::......
Mosquito   458 A--LHPNESIVSYAMPYLVELGKIL-----RDTDRRIVHNYAIWRLVMSIMTHMIDDYQKERVEF 515

  Fly   434 RKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLT 498
            |:.|:|.......|..||..||..:|.||||:|:|..|:.|||..|..||..|||||...|.::.
Mosquito   516 RRKLLGIQSERNRWSQCVEWTNKKLGMAVGALFIRDNFNQESKETALTMIHTIREAFNELLADID 580

  Fly   499 WVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKR 563
            |:|.:||..|.|||:.:::.||:||.:.:..||:|:|..|.|....:.||.:.:..:..:.||:.
Mosquito   581 WMDDETRAVAKEKADAMNERIGYPDILTNADELEKEYVNLTIHGGLFLENILSILKWEAERNLQL 645

  Fly   564 LDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAF 628
            |.:||:|..|...|..|||:|.|.||.|||||||||..|:..|.|||||:|.:|||:|||:||.|
Mosquito   646 LRKPVDKNKWATEPAVVNAFYNPNKNDIVFPAGILQPLFYSQNFPKSLNYGGIGVVIGHEITHGF 710

  Fly   629 DDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMN--GRTLNGKQTLGENIADNGGLK 691
            ||:||::||.||:.:||::.:|:.|.|:::||..|||.||::  |..::|:.|.|||||||||||
Mosquito   711 DDKGRQFDKDGNMMQWWNNATIKTFRERAQCIIDQYSRYKIDEVGLYMDGRMTQGENIADNGGLK 775

  Fly   692 AAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVI 756
            .:|.||::..|....: ..|||||:||.||||:::||:||.|...|..|.::....|||...|||
Mosquito   776 QSYRAYRKWVSQHGSE-PDLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSSVHSPGIIRVI 839

  Fly   757 GTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            |.|||.::|||.::|..|..|||..||.||
Mosquito   840 GPLSNSRDFAEAYRCPLGSPMNPVSKCSVW 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	258/662 (39%)
Nep1	XP_553645.4	None