Protein Alignment Nep3 and kel

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_068070210.1
• Gene: kel / 101882278
• ZFINID: ZDB-GENE-110411-118
• Length: 793
• Species: Danio rerio
• Alignment Length: 796
• Identity: 197/796 - (24%)
• Similarity: 325/796 - (40%)
• Gaps: 140/796 - (17%)

  Fly    54 LLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQ----PHQKDCPSGNELPCLNKHCIFASSE 114
            ||:..|.:::....|.:.:::            |:|    |.:....|...| ||:..||.||..
Zfish    72 LLLPPFAVSLFATALGLGIYS------------HLQKTADPWKSKWKSAAPL-CLSPACIRASEH 123

  Fly   115 ILKSIDVTVDPCDDFY------GYSCN---QWIKNN-------------PIPEGKSTWG------ 151
            ...::|....|||.|.      |.|.|   |.:|..             .:..|...|.
Zfish   124 FSVAMDPFSRPCDYFLFACGAGGSSTNRDRQRVKGEVNKHSEVRTRGLIEMRRGTDGWSKSDGQL 188

  Fly   152 -TFGKLEQMNQLIIRNVLEKPAKSFK-SDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGG 214
             ||...:......|:.:||.|.::.. ..||:|||.:::||::| |..||:|::|...||.|:||
Zfish   189 KTFPDRQTALLTAIKEILEAPDEAVSMGAAEQKAKNFFKSCMNA-ESREKMGSEPFLTLLQQLGG 252

  Fly   215 WNVTKSGYNVANWT-MGHTLKILHNKYN----FNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTA 274
            |.|:    .|.|.| ...||.:|..:|:    ||...|....|:...|:||.||||:.....|..
Zfish   253 WAVS----GVWNQTDFNSTLALLMGQYSTFPFFNVYVGPEPSEEQSASNRHYIQIDEPHFQFPIE 313

  Fly   275 DYYNNKTDNHRKVLNEYIEYMTKVC----VLLGANESDARAQMIGV-INFEKKLANITIPLEDRR 334
              :|:||.. .|....|:......|    ||||. .||...|..|: ::....||..|.||..|.
Zfish   314 --WNSKTQK-AKANTRYLRPFYSACGQYLVLLGV-PSDRTTQHCGLFVSLSTTLAVATFPLPYRL 374

  Fly   335 NEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQT 399
            :::.:|....:::|..|||.::|........|.:  .::..::|:|:...::.::|..|...:..
Zfish   375 SQKLLYRRTTIQELQTLAPAVDWLACLQATFQPL--LISKSDIVLVHNLPYIIHMSKTIHLWQVQ 437

  Fly   400 EE--GKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEI--WRYCVSDTNNVVGF 460
            .|  |...||.|:::..::||...|...|   ::.:|...:.:...:|:  |..||..|..  ||
Zfish   438 HELMGTGPLNTYMIFSLLQTLIPALDSRF---FQIMRNYSIATGDTQEMPHWWRCVQQTER--GF 497

  Fly   461 AVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYI 525
            ........:..|.:.:  ||::|.::..:.|..|.:|:|.|::..:..:.|.|.::..|......
Zfish   498 DTLLSHAIREKHAQKE--AEELIQDVYSSLKKKLTDLSWRDEKESDFILNKINSLNPRISTNTNN 560

  Fly   526 LDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQ 590
            |...||:..|.::.:....:|.|.:|:.:...||..:.|..........|||..       :.|.
Zfish   561 LSYTELNHLYEKVILNEEDFFSNYLQILLLEQKSRARLLSLGTQTEGLSMTPFI-------SGND 618

  Fly   591 IVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINR------------ 643
            |:.|.|:..:|||..:.|::||:|.:|.:|..:|.|.....  .|.|..|...
Zfish   619 IIVPVGMFVSPFFHSSYPRALNYGTLGSLMAKDLLHLLLPD--IYTKAKNPETESLCVWSHYLSV 681

  Fly   644 -----WWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSD 703
                 |.|:..:.  :.|.:.:..|||..::                   .|.|...:::|..:|
Zfish   682 TKGPGWGDAFYLP--SSKQQEVWVQYSALQV-------------------ALDAYKMSFKRYLAD 725

  Fly   704 RDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEV 768
            .     .|||.:..|  ||..||.:|.|.  ||    ...|..|..|| |.|....||.....:.
Zfish   726 S-----SLPGFSYVH--LFLSSFTKVTCD--TD----AYREFMPLEPS-FLVTVLCSNSGLCPKP 776

  Fly   769 FQCKPGKRMNPTEKCE 784
            ..|....:..|.|.|:
Zfish   777 LTCMNKPQSFPAEMCQ 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	180/721 (25%)
kel	XP_068070210.1	GluZincin	133..>654	CDD:472708	143/545 (26%)
		GluZincin	617..>755	CDD:472708	41/173 (24%)