Protein Alignment Nep3 and mme

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 762
• Identity: 246/762 - (32%)
• Similarity: 397/762 - (52%)
• Gaps: 62/762 - (8%)

  Fly    51 EKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEI 115
            ||.|:|....:.|....:::...|                       .|:..|.::.||..::.|
 Frog    21 EKGLIILCIFLGIISIAMILAYAT-----------------------SNDGICTSQACISTAARI 62

  Fly   116 LKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAE 180
            :.::|...|||:|||.|:|..|:|.|.||:......||..|....::::::.|||.:.. ...|.
 Frog    63 IANMDAATDPCNDFYQYACGGWLKKNRIPDNNIVSNTFDILRTDIEVVLKDALEKESAD-DIPAI 126

  Fly   181 RKAKVYYESCLDAD-EHMEKLGAKPMNDLLLQIGGWNVT----KSGYNVANWTMGHTLKILHNKY 240
            :|.|.:|:||:|.. :::.|.|  |:...|..:..|.:.    ::.|.:. |:...::.....||
 Frog   127 KKVKTFYKSCIDETIKNLRKGG--PLIKTLPALYDWPIAVDNWETRYGLV-WSAQESIAGFITKY 188

  Fly   241 NFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVL---- 301
            ..:.|....:.||..|||.:::.|||.||.||:.|||:.|..:....| .|:|.|..|.:|
 Frog   189 GQSGLINVYVSEDLTNSSTYILHIDQPGLGLPSKDYYDCKGTSEIACL-AYMEQMVSVAMLIRKE 252

  Fly   302 --LGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPF------LNWT 358
              |..||....::|..|...|:::|......|.|.|...:|..|.|..::|..|.      :||.
 Frog   253 RNLTINEDKILSEMEKVFKLEREIAKAEASEEIRENLNDIYKKMTLSGIAKTYPLKMNDQNINWL 317

  Fly   359 DHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLS 423
            ...:..:...|..:.::|.|.:...|:||.|.  .|...:..|    |.|||.|:.:.:..:.||
 Frog   318 KLINAIISPGGVSIEENEQVALICSDYLKKLR--FLNKYKARE----LQNYLGWRYILSAINDLS 376

  Fly   424 KPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAF-----HGESKPAAEQMI 483
            ..:::....::|||.|:......|:.||:..|:.:..|:|.:::::..     |.:.|...:::|
 Frog   377 LEYKNTGIHLKKALYGNAAEGSDWQTCVTYLNDNMEDAIGRLYLKETLSADIEHVKVKDKVKEII 441

  Fly   484 AEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFEN 548
            ||||.||...|:.:.|:|:.|:::|..|...|::.|.|.:.|:|..:|::.|:||....:..|||
 Frog   442 AEIRRAFLEMLEEMDWMDEDTKKRAARKVASINERIAFSEDIMDDFKLNEGYSELEFRVDELFEN 506

  Fly   549 NIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNF 613
            ..:...:..|....||.:.|||..|...|..|||:|:.|.|:|||||||||||||..:.|.:||:
 Frog   507 KQKYIEFVQKKMTSRLRKQVNKNEWVPGPAHVNAFYSLTYNEIVFPAGILQTPFFSSSQPSALNY 571

  Fly   614 GAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY---KMNGRTLN 675
            |.:|:::|||:||.||::|..:|:.||:..||.:.|:..|:..|:|...||..|   :..|:.||
 Frog   572 GGIGMIIGHEITHGFDNRGCNFDEHGNLVNWWTNASMMNFSNLSQCFVNQYGNYSWDEAGGQYLN 636

  Fly   676 GKQTLGENIADNGGLKAAYHAYQR-TKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETN 739
            |..||||||:||||::.||.|::. .||.::.|:  |||::|...||||:||.|:||.....|..
 Frog   637 GISTLGENISDNGGIRGAYRAFKNYVKSHKEDDL--LPGIDLDSDQLFFISFGQIWCGMHRPEYA 699

  Fly   740 LLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            ...::...|:|..|||||||.|..||::.|.|.....|||..||::|
 Frog   700 ATLIKTGSHTPGIFRVIGTLQNSPEFSKAFSCCNNAYMNPAVKCKLW 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	232/686 (34%)
mme	XP_031758820.1	M13	71..744	CDD:341056	232/685 (34%)