Protein Alignment Nep3 and ecel1

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 791
• Identity: 281/791 - (35%)
• Similarity: 433/791 - (54%)
• Gaps: 51/791 - (6%)

  Fly     8 EFTE-------DDSSSI-GGIQLNEATGHTGMQIRYHTARATWNWRSRNKTEKWLLITTFVMAIT 64
            ||.|       :.||:: .|..|..::       :..|.:....| ||.:|   .|::..|.|:.
 Frog    13 EFQEVKYVSKYNSSSTLSNGFNLQVSS-------KKQTKKVVPRW-SRRET---CLLSGLVFAVG 66

  Fly    65 IFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIF-ASSEILKSIDVTVDPCDD 128
            :..:|       |.....|::...|..|  |..|    |..:.... ||..|..:||.|:.||.|
 Frog    67 LCVIL-------GCMLVLKYLSMEQDVQ--CLEG----CQERKAFMRASKFITNNIDPTISPCTD 118

  Fly   129 FYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPA-KSFKSDAERKAKVYYESCLD 192
            ||.::|..|::.:.|||.|..:||...:.:.|:..:.::|.:|. :..|..||||.|.:::|||:
 Frog   119 FYSFACGGWLRRHGIPEDKLIYGTIAAIGEQNEEKLEHLLLQPVRRKHKGSAERKVKEFFKSCLN 183

  Fly   193 ADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNS 257
            ..: :::|||:||..::...|||::.:...  ..|.....|......|:....|...:..|||||
 Frog   184 MRD-IDRLGARPMLQVIEDCGGWDLPEDPR--TQWDFNELLYKTQGVYSTAVFFSMTVSLDDKNS 245

  Fly   258 SRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKK 322
            ||::|:|||.|||||....|..:.:...|||..|..:|..:..|||......:|:.|  ::.|:.
 Frog   246 SRYIIRIDQDGLTLPERTLYLGQDEESIKVLEAYKVFMQTILSLLGVENVQKKAEEI--LHLEQH 308

  Fly   323 LANITIPLED--RRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDF 385
            |:||||...|  ||:...||:.:.|.||.::.|.|||.:..:   ::......:||.|||.|.|:
 Frog   309 LSNITISEFDDMRRDISTMYNKVTLAQLQQITPHLNWKNLLN---RIFHTNFPEDEEVVVLATDY 370

  Fly   386 LKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYC 450
            ::.:|::|.....:     .|:||::|:.|..|:..||.|||||...:.|.:.||:...|:.:.|
 Frog   371 MQKVSEMIRSTPAS-----VLHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGSEKQAELTKVC 430

  Fly   451 VSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQI 515
            ::..|...|.|:||:||.:.|...||...:|::..|:......|:.|.|:|.:|::.|.||...:
 Frog   431 LTQANKHFGMALGALFVEEYFSSSSKAKVQQLVENIKHILDYRLEELDWMDTETKQAAREKLKHM 495

  Fly   516 SDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTV 580
            ..|||:||.:|.|..:||:| |..:....||:|.:....|::|..::|:.|.|:|:.|.:.||.:
 Frog   496 MVMIGYPDVLLQPESMDKEY-EFEVNEKTYFKNILNSIRYSIKMAVRRIRQEVDKSAWLLPPQAL 559

  Fly   581 NAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWW 645
            ||||.|.|||:||||||||...:|.:.|:|||:|.:|.::||||||.:||.|.:||..||..:||
 Frog   560 NAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDANGNPIQWW 624

  Fly   646 DSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILK 710
            ...|..:|.:|:|||...|..:.:..:.:||:.||||||||.||||.||:|||:...|...: ..
 Frog   625 TEDSYSKFLKKAECIVDLYENFTVYNQRVNGRTTLGENIADLGGLKLAYYAYQKWVRDNGPE-RP 688

  Fly   711 LPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGK 775
            ||.|..||.||||::|||.||.....::..||:..|.|:|..:||:|::|..:||..||.|....
 Frog   689 LPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNS 753

  Fly   776 RMNPTEKCEVW 786
            .|||..||.||
 Frog   754 PMNPVHKCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	249/663 (38%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	249/663 (38%)