Protein Alignment Nep3 and ece2

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 798
• Identity: 336/798 - (42%)
• Similarity: 484/798 - (60%)
• Gaps: 55/798 - (6%)

  Fly     1 MTRYKQTEFTEDDSSSIGGIQLNEATGHTGMQIRYHTARA--TWNWRSRNKTEKWLLITTFVMAI 63
            |:.||:..|.::|.....|   ..||....:::.:...|.  ......|::.|..|...:.|:.:
 Frog    12 MSDYKRATFHDEDVPEPTG---EGATSPDTVEVGFRKGRGHILGALGGRSQPEVLLGALSAVLGV 73

  Fly    64 TIFTLLIVL----FTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVD 124
            .:...||.|    .||...|                      .||::.|:..:..||.|:|..:|
 Frog    74 LLLGSLIALGVQQMTDRSRS----------------------LCLSEACVSVAGRILDSLDRGID 116

  Fly   125 PCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYES 189
            ||.|||.|||..|::.||:|:|:|.|.||..:...||.|::::||....:..|:||.|.:.:|.|
 Frog   117 PCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLS 181

  Fly   190 CLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANW---TMGHTLKILHNKYNFNCLFGWAIG 251
            || .::.:|:|..||:.||:.:|||||::      .||   .....||.:...|.....|...:.
 Frog   182 CL-KEQRIEELRQKPLTDLIEKIGGWNIS------GNWRGENFMSVLKTVSGTYRATPFFSVFVS 239

  Fly   252 EDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGV 316
            .|.|:|:.::||:||.||.||:.|||.|||.| .|||:.|::||..|..|||.:......||..:
 Frog   240 ADSKSSNSNIIQVDQSGLFLPSRDYYLNKTAN-GKVLDAYLQYMVSVGELLGGSPGSVDMQMTQI 303

  Fly   317 INFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVY 381
            :.||..|||:|:|.::||:||.:|:.|.:.:|..|||..:|.|:...|:..:.  :.|.|.||||
 Frog   304 LEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFALSPLD--LNDTEPVVVY 366

  Fly   382 APDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGG-EE 445
            ..::|:.:|:::     .....:.|||||||..|:.::|.|...|..|...:.::|.|:... ..
 Frog   367 GKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTP 426

  Fly   446 IWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIE 510
            .|:.|:|:|::.:|||:|::||:..|...||..|||||:|||:||::.|..|||:|::||..|.|
 Frog   427 RWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKE 491

  Fly   511 KANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGM 575
            ||:.|.|||||||:|||..|||:.|....::.:|:|:|.:....::.|...::|.:|.|:..|.|
 Frog   492 KADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSM 556

  Fly   576 TPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGN 640
            |||||||||.|.||:|||||||||.||:...:||:||||.:||||||||||||||||||||:.||
 Frog   557 TPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGN 621

  Fly   641 INRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQR--TKSD 703
            :..||.:.|:|.|..::||:..||:.|.:||..:||:||||||||||||||||||||:.  .|..
 Frog   622 LRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHG 686

  Fly   704 RDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEV 768
            .:   .:|||:.||::|||||.|||||||..|.|::...:..|||||::|||||||||.|:|||.
 Frog   687 EE---KQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEH 748

  Fly   769 FQCKPGKRMNPTEKCEVW 786
            |.|..|..|||.:.|:||
 Frog   749 FNCPKGTPMNPGKHCDVW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	307/666 (46%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	307/665 (46%)