Protein Alignment pico and Apbb1ip

DIOPT Version :9

• Sequence 1: NP_608363.1
• Gene: pico / 33003
• FlyBaseID: FBgn0261811
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001094047.1
• Gene: Apbb1ip / 307171
• RGDID: 1304795
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 946
• Identity: 227/946 - (23%)
• Similarity: 349/946 - (36%)
• Gaps: 337/946 - (35%)

  Fly   113 PLTPEAKQLSHTYRISMANLEDS----QESELDQILGELSLLEAQISYTEASMLPAMCAPSAGAQ 173
            |..|:..:....:.:...:|.:|    ::.:||.::.:   |.|.||..|...:.|
  Rat    33 PAEPKPPREEFNFSVGFKDLNESLNALEDQDLDALMAD---LVADISEAEQRTIQA--------- 85

  Fly   174 IAPPPGVTQLPGSAPTMVSMSASSSRSHSRTNSTISADVSSCSSSGISENGHGLGLVLGGPGSAG 238
                              ...:|.::.|       ||.:.:....|.:..|:|............
  Rat    86 ------------------QKESSQNQGH-------SALLEASDGQGTAPRGYGANAAAFDVSDYE 125

  Fly   239 MMVQPPPPGGMTMGITLGVVTPREPRTESPDNDSAFSDTVSLLSSESSASSNTSLQQQQQQQQQQ 303
            ..:.|||...|     |.::.|..|....|            ||.|..
  Rat   126 EALPPPPADPM-----LDLLPPPPPPPPKP------------LSKEEE----------------- 156

  Fly   304 HHQHQQHHQHQQQQQKPQLAGAEKLHHHGVHGQHGGQQSGANSITKADKIQLALHKLESAPIRRL 368
                                                     .::.|||||:|||.||:.|.:::|
  Rat   157 -----------------------------------------EALAKADKIKLALEKLKEAKVKKL 180

  Fly   369 FVKAFTSDGASKSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDN 433
            .||....|.::|||:||||.....|...|.:|.|.....:|.|.|...:||:||:|||||.:|:.
  Rat   181 VVKVHMGDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERIFEDHENVVEV 245

  Fly   434 LMTWHSDAGNRVLFQQRPDKVTLFLRPE-LYLPGPQMAPGCQHDEQTRQM-------LLDEFFDS 490
            |..|..|..|||||.::.:|..:|..|: .||..    .|.:..|...:|       ||:|.|..
  Rat   246 LSDWTRDTENRVLFLEKEEKYAVFKNPQNFYLDN----KGKKEKESNEKMNAKNKEYLLEESFCG 306

  Fly   491 HNQL--QMDGPLYMKADPKKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFHGHNVYTGLGW 553
            .:.:  :::|.||:|.|.||.|||.:|:||:||:||.||.|||.:|||||...|...|:|.|:..
  Rat   307 TSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGIQC 371

  Fly   554 RKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLE 618
            :.|:|:|||:.|..|   ...:.|..:.:|.||.:|..||.:|:..||:.||||.|:|:::.
  Rat   372 KMKYKAPTDHCFVLK---HPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYDNYQR--- 430

  Fly   619 DLCLSRDDAVSQSSFAASMRSESISSISSAVPSQCGSVSSAISSMSNSTSGRTSRASSSSSSGCL 683
                    ||:::..|:...:..    ::..|:|   .::.:.:.::..:|...:|:.|..
  Rat   431 --------AVARAGLASRWTNLG----TATTPAQ---PAAGLKTGTSQPNGPMPQAAPSPG---- 476

  Fly   684 SDDNNAFDSEFTTGTIKRKPSMKPNLPLTTMTRQLKEVGEITICESAGGDASSPERSGTLTRRHS 748
                               |.::..|..|..|:.                    |:.|  ...||
  Rat   477 -------------------PPLRETLTQTETTKD--------------------EKQG--LANHS 500

  Fly   749 RRKSQESNGSGTLKRRPIAVPVATVVKQTEPMGSASSTSSSSNSTPTPTPSICAKP--PPGDSAS 811
            ...|:|::.           |.::::....|:..:|.|              |..|  ||.....
  Rat   501 PGASRENHR-----------PKSSLLPPPPPVRRSSDT--------------CGSPALPPKAKGP 540

  Fly   812 LMCSSTLSLDS-LPPPPPPPALDGSEDQDVYGSQLSLASLPPPPPPEDVLAMNYA-EPSSPSTPT 874
            ..|:.|...:: ||||||||.   .||.:   |.|    ||||||      :.|. ||
  Rat   541 GSCTFTAQPENFLPPPPPPPP---QEDDN---SML----LPPPPP------LAYLDEP------- 582

  Fly   875 PMSTPMIMPNSNGSLPPAVPAKPMKPAVKQAAGGLKAAPPYKAPPDYVGPALLPGPPLPPPPPAQ 939
                           |..||..|                    ||..|..:.||.|  |||||..
  Rat   583 ---------------PDFVPPPP--------------------PPATVEDSALPPP--PPPPPCL 610

  Fly   940 KKVSFADSPVLLRRKMCSPEPVLPQRSPSTTLSCHSSSSAGSAYQTYAPGPMLPPRADVARLSSL 1004
            .:.....|| |..:|:    ||.|:|..:..|                ||   .||
  Rat   611 SQEMTKSSP-LPAKKL----PVPPKRQENQGL----------------PG---APR--------- 642

  Fly  1005 SNGSSSEVTSPKRLQESASNPPRDFLKDLQRVMRKK 1040
                               |..:||:.||.:.::||
  Rat   643 -------------------NTEQDFMSDLMKALQKK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pico	NP_608363.1	GRB7_RA	364..451	CDD:176382	36/86 (42%)
		PH_APBB1IP	489..614	CDD:269961	54/126 (43%)
		PH	494..605	CDD:278594	48/112 (43%)
Apbb1ip	NP_001094047.1	RA_MRL_RIAM	185..266	CDD:340554	33/80 (41%)
		PH_APBB1IP	308..429	CDD:269961	54/123 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351281
Domainoid	1	1.000	105	1.000	Domainoid score	I6512
eggNOG	1	0.900	-	-		E1_KOG3751
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2739
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005410
OrthoInspector	1	1.000	-	-		otm46447
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.850