Protein Alignment Hers and AT3G48060

DIOPT Version :10

• Sequence 1: NP_608360.2
• Gene: Hers / 33000
• FlyBaseID: FBgn0052529
• Length: 2529
• Species: Drosophila melanogaster
• Sequence 2: NP_001327753.1
• Gene: AT3G48060 / 823961
• AraportID: AT3G48060
• Length: 1612
• Species: Arabidopsis thaliana
• Alignment Length: 1527
• Identity: 286/1527 - (18%)
• Similarity: 466/1527 - (30%)
• Gaps: 537/1527 - (35%)

  Fly     3 SKKRSNAAERVQRSTATAAAAAAAAAAAATASSTQGKKRPGKQTKAS--GGGGDEADDKKS---- 61
            |.|.|...::. ||..........|...|.:.|.||...||:.:...  .||..||:...|
plant   389 SHKNSEIGKKA-RSLVDTWKKRVEAEMDAKSGSNQGVSWPGRLSHGGRHSGGSAEANKTSSSHLH 452

  Fly    62 ASK----------------TDSAAKKPAKDPTGSSGVSTATTEGGAGNGGGKQTTSTTTSSTSST 110
            |||                |...:.:.|..|.....||....:..||.||..:..:......||
plant   453 ASKSVSVKQQVENNLKCVATSPGSTRSAPSPGSGGNVSKDGQQRNAGAGGVSEVLAAVKDEKSS- 516

  Fly   111 TAPSASASASASNSLKLSPEER-------HEDGKARAINKMLKSLDIKIHGFDNLLPSGEERLND 168
                 |:|.|.:||...|.|..       .||.::......||    |..|     .|...|.::
plant   517 -----SSSQSHNNSQSCSSEHAKTGNLCGKEDARSSTAGSTLK----KCSG-----GSSRHRKSN 567

  Fly   169 GVLKSSISENVKTKSRAAAVKVISSLNPGKMPPVKRVRPSPEPVREKVAEKP-----AEKVLDKE 228
            .|.:.|.|   ....|.|.:.  .|.:..:..|.:::..| ....||..|.|     ..|::.|
plant   568 NVFQGSSS---SASPRGAGLS--RSFSSHRNVPSEKISQS-SLTSEKTLEVPLTEGSGNKLIVK- 625

  Fly   229 KPKAE---QQIT----PPPAPEESPASKVPKKTVQQ------------AKKAKVESSLVQA---- 270
            .|:..   |.::    ..|||..|..|. |..||:|            :.:|.| ||::.|
plant   626 LPRGRSPAQSVSGGSLEDPAPVNSRVSS-PVHTVKQELCDNNWREKNHSYRADV-SSVLNAESWQ 688

  Fly   271 -----TVLTTTSAATSAP-SSASTSKHTSTKNPGKKSAHSEQMPK--KELSKLAKMGKPKKEAN- 326
                 .:||.:..||.:| ..|...:..:.|:..|.|.:.:....  .|.....:.|......|
plant   689 SNELKDILTGSQEATGSPLVVAGDEREGALKDSDKASGNVKATSSLGNEFKSGERHGGTLSSMNA 753

  Fly   327 LVKSTARLPDSN-----TESVQMELEEIVSTPTVTPTPSATPTATPTPTATPTLTPTPTATRTRT 386
            |::|..|..::|     ::.|.|.|...|:...::.:|.|:|:.:..|.:......|
plant   754 LIESCVRYSETNASLAGSDDVGMNLLASVAADEMSKSPVASPSVSQPPNSLMNENST-------- 810

  Fly   387 PTPTLTPTPTPTSTPSSTAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSKGRMQQALNQKAPA 451
                         ..::|.:.|....|        .||...|:.|.::           .|....
plant   811 -------------VGNNTKLMASDGLP--------HKQHQAVRPTLSN-----------EQGEQH 843

  Fly   452 ASWSGAKDIYDFKSGSEDEEPIKMVLPSLKELREFSD---EDNK-----------PLKLFER--- 499
            .|.||.:...:.|:.|:..:.:|......::|:.|.|   |.|:           |.|:.:.
plant   844 VSSSGTQLESEIKNESKTGDRVKSSNSDTEDLQRFVDQRLESNENSDGVVASPPLPTKVIKENIL 908

  Fly   500 ------QAEKTKVQVQDE-------------------------------EEQPLV-----KKEEK 522
                  :.:..|..|:.|                               |..||.     |||||
plant   909 DDSDSGEVKDIKTDVKSEADCTSDLTKRVASSMLTECRDVSKMVDSVAVEHTPLEGVDDDKKEEK 973

  Fly   523 PPSEKEVKVKSKEKEKEKEKDVDPLSN--AQQSEPAAKHTTSTSTTSTTSITSVKKQAKRKIATP 585
            ||:     ..|.|..|:.|:|| |:|:  ::..:..:.....|...:..:...:.::..:||...
plant   974 PPT-----ALSSELVKKVEEDV-PVSSGISRGMDAVSIDRPITEMVNNIAFNHMDQKDIKKIKQD 1032

  Fly   586 MPSSAGRKK-------KTVGKGKAAAAK-----------------EPPPSGSSAESSSSEDERKL 626
            ..:|.|..|       .:|.|||....:                 .|..|...||.....:..|.
plant  1033 FDTSVGAVKDASAGLDSSVTKGKVEPVEGNLENIEIMERYSGLRATPGLSPKEAEDLKRPNAPKT 1097

  Fly   627 SAYSGPK-------RHRMASLNALAKVQCLYENESRTAHELGLSKATQQPPRIRTLDGSDDDNHK 684
            |...|.:       ....:|::|.|......|.::|...:|.              :|.|.|:
plant  1098 SDADGDEAGECTSAARDASSVSAAASASAGSEMDARVEFDLN--------------EGFDGDD-- 1146

  Fly   685 DSPRHGDTDRDKGSVSPPHTSAAP------PAAPIA------------------PPKEAEPRREL 725
              .:|||::...|||....|...|      |.||::                  ||::.     |
plant  1147 --AQHGDSNNFSGSVVLTPTPLQPVNTLPFPVAPVSSGIPASITVAAAVKGPFVPPEDL-----L 1204

  Fly   726 RY--VPGGRGVGKHWEFDSDSETEELQLQQTLPPVKKKKLPKKAPPKKVASSETDAKRKKKSVQV 788
            ||  ..|.||......|   ...|..:.|..|..:           ...::|:......|::...
plant  1205 RYKGAVGWRGSAATSAF---RPAEPRKAQDVLLSI-----------NNTSTSDASTSAGKQTRTF 1255

  Fly   789 EESD----DEEAKEKEKEKEKPKPPKQLPKKRKTAFTEELIGDYKGILARKRMASLNASAIVAAT 849
            .:.|    ||...|....:....|         |..|..:..::..:.:....::|:.|:
plant  1256 LDFDLNVPDERVLEDLASQRSGNP---------TNCTSGITNNFDQVRSGVMGSALDHSS----- 1306

  Fly   850 YEVERHLDKNLASDCSSFESYDELDTMPTTTSKVTSAAAIKTEVIHIKKEPKESKESLRERERER 914
                ..||.|...|.:...||    ||.::....:|...:|.        |...
plant  1307 ----GGLDLNKVDDLTDMNSY----TMNSSHRLDSSFQQVKL--------PSTG----------- 1344

  Fly   915 ESERRRERDNELKDSTVGKMSSHSIIEESNDSKYSKETKETNTDTTITTTGYRDSAASTKDAKDC 979
                 ..||.:|.|..||                                   |.||
plant  1345 -----GRRDFDLNDGPVG-----------------------------------DDAA-------- 1361

  Fly   980 SRPTSSSVVIVQ------DTDVTITGVYVNASNGA-------AQEAYCKMQYRVQSSVTEERVLR 1031
               ...|:|:.|      .:..:::|:.||..|.|       |..||..:.   ...:..||..:
plant  1362 ---VEPSMVLNQHSRSGLPSQPSLSGIRVNGENMASFSTWFPAANAYSAVS---MPPIMPERGDQ 1420

  Fly  1032 P----GSVEPPKSYTPLSALSSMLPPGASSGLSEAHSSPPLPVHAAPTGPHVLLPGEHLSAGMYH 1092
            |    .:..|.:...|.:.:||..|.|....:  ..|||.:|..:. |..:.:.|
plant  1421 PFPMIATRGPQRMLGPTTGVSSFSPEGYRGPV--LSSSPAMPFQST-TFQYPVFP---------- 1472

  Fly  1093 APDLGLHTEHALPDHHGPPPPSYAAAAAAAAAAAAYHAHQLAPGGGGVLHMHHQHQYAAHAAHAH 1157
               .|    ::.|    ..|.::..|:.|                         |..::.:..|:
plant  1473 ---FG----NSFP----VTPANFPGASTA-------------------------HMDSSSSGRAY 1501

  Fly  1158 HYQQAAEYHGGPPPPPHHYGGPPPQGHYGPPPGAPVPVPVAVPNTVTVPPERCDVGSPPPSYRAS 1222
            .....::..|                     ||.|||                           |
plant  1502 FPGVNSQILG---------------------PGVPVP---------------------------S 1518

  Fly  1223 AYPPPSSVGMPPPTLGGG---SSAFCAPSPLHHHQHQHQQPGPGVGPPHHDPSGYYQPAGPLISP 1284
            .||.|..||:|.....||   :||....|.|..:.          ||..|:..|  :....|:|.
plant  1519 NYPRPYIVGLPNGGSNGGVLDNSAKWFRSGLDLNS----------GPGGHETEG--RDESTLVSR 1571

  Fly  1285 HVIAAPPPPAQ------------VKKLQEEDG 1304
            .:.::...|::            |.|.:|.:|
plant  1572 QLSSSASVPSKEDQARMYQMSGGVLKRKEPEG 1603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hers	NP_608360.2	BAH_BAHCC1	2366..2519	CDD:240065
AT3G48060	NP_001327753.1	BAH	48..174	CDD:470629
		TFS2N	333..412	CDD:197766	5/23 (22%)
		TFSII	363..>513	CDD:273592	29/124 (23%)