Protein Alignment Hers and SUO

DIOPT Version :10

• Sequence 1: NP_608360.2
• Gene: Hers / 33000
• FlyBaseID: FBgn0052529
• Length: 2529
• Species: Drosophila melanogaster
• Sequence 2: NP_190388.2
• Gene: SUO / 823960
• AraportID: AT3G48050
• Length: 1613
• Species: Arabidopsis thaliana
• Alignment Length: 1630
• Identity: 317/1630 - (19%)
• Similarity: 511/1630 - (31%)
• Gaps: 543/1630 - (33%)

  Fly    54 DEADDK---------KSASKTDSAAKKPAKDPTGSSGVSTATTEGGAGN-------GGGKQTTST 102
            |..||:         |:.|:..:..::..:.|...:..:|:..:.|..|       |.|::....
plant   167 DYIDDRQLEVDKLLCKTRSEMHTTLQQGGRSPKSMNSPTTSQPKDGIQNSNSFLSQGKGRKRERM 231

  Fly   103 TTSSTSSTTAPSASASASASNSLKLSPEERHEDGKARAINKMLKSLDIKIHGFDNLLPS-GEERL 166
            ...|.|.....|:....|.|..|      |.|.|        |||..:|......|:.| |.|:|
plant   232 DHGSESVKRERSSRVDDSGSGPL------RTESG--------LKSEILKFTEKGGLVDSEGVEKL 282

  Fly   167 NDGVLKSSISENVKTKSRAAAVKVISSLNPGKMPPVKR-VRPSPEPV-REKVAEKPAEKVLDKEK 229
            ...:|.....:.:....||....|:::.:  |...:.| |:....|| .|.:.|....||.|...
plant   283 VQLMLPERNEKKIDLVGRAILAGVVAATD--KFDCLSRFVQLRGLPVFDEWLQEVHKGKVGDGGS 345

  Fly   230 PKAEQQITPP------PAPEESPAS-------KVPK--------KTVQQAKKAKVESSLVQATVL 273
            ||...::...      .|.::.|.:       .:.|        |..:..|||:   |||.
plant   346 PKDSDRLVDDFLLVLLRALDKLPVNLNALQTCNIGKSVNHLRSHKNSEIGKKAR---SLVD---- 403

  Fly   274 TTTSAATSAPSSASTSKHTSTKNPGKKSAHSEQMPKKELSKLAKMGKPKKEANLVKSTARLPDSN 338
             |......|...|.:..:.....||:            ||...:......|||.. |::.|..|.
plant   404 -TWKKRVEAEMDAKSGSNQGVSWPGR------------LSHGGRHSGGSAEANKT-SSSHLHASK 454

  Fly   339 TESVQMELEEIVSTPTVTPTPSATPTATPTPTATPTLTPTPTATRTRTPTPTLTPTPTPTSTPSS 403
            :.||:.::|.  :...|..:|.:|.:|                           |:|......|.
plant   455 SVSVKQQVEN--NLKCVATSPGSTRSA---------------------------PSPGSGGNVSK 490

  Fly   404 TAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSK--GRMQQALNQKAPAASWSGAKDIYDFKSG 466
            ........|      ||..:....||..|:|:.|:  ...|...::.|...:..|.:|.....:|
plant   491 DGQQRNAGA------GGVSEVLAAVKDEKSSSSSQSHNNSQSCSSEHAKTGNLCGKEDARSSTAG 549

  Fly   467 SEDEEPIKMVLPSLKEL-----------------------------REFSDEDNKPLKLFERQ-- 500
            |           :||:.                             |.||...|.|.:...:.
plant   550 S-----------TLKKCSGGSSRHRKSNNVFQGSSSSASPRGAGLSRSFSSHRNVPSEKISQSSL 603

  Fly   501 -AEKTKVQVQDEEEQPLVKKEEKPPSEKEVKVKSKEKEKEKEKDV------DPLS-NAQQSEP-- 555
             :|||.       |.||.:     .|..::.||...:.:...:.|      ||.. |::.|.|
plant   604 TSEKTL-------EVPLTE-----GSGNKLIVKLPNRGRSPAQSVSGGSLEDPAPVNSRVSSPVH 656

  Fly   556 AAK------------HTTSTSTTSTTSITSVKKQAKRKIATPMPSSAGRKKKTVGKGKAAAAKEP 608
            |.|            |:...:.:|..:..|.:....:.|.|....:|| .....|..:....|:.
plant   657 AVKQELCDNNGREKNHSYRPNVSSVLNAESWQSNELKDILTGSQEAAG-SPLVAGDERGGDLKDS 720

  Fly   609 PPSGSSAESSSSEDERKLSAYSGPKRH--RMASLNALAKVQCLYENESRT----AHELGL----- 662
            ..:..:.:.:||..    :.:...:||  .::|:|||.: .|:..:|:..    :.::|:
plant   721 DKASGNVKGTSSLG----NEFKSGERHGGTLSSMNALIE-SCVRYSETNASLAGSDDVGMNLLAS 780

  Fly   663 ------------SKATQQPP--------------RIRTLDGSDDDNHKDSPRHGDTDRDKGSVSP 701
                        |.:..|||              ::...||...:.|:.......|::.:..||.
plant   781 VAADEMSKSPVASPSVSQPPNSVMNENSTVGNNTKLMASDGLPHEQHQAVCTSVSTEQGEQHVSS 845

  Fly   702 PHTSAAPPAAPIAPPKEAEPRRELRYVPGGRGVGKHWEFDSDSETEELQ--LQQTLPP------- 757
            ..|..           |:|.:.|.:  .|.|      :..|:|:||:||  :.|.|..
plant   846 SGTQL-----------ESEIKNESK--TGDR------DKSSNSDTEDLQRLVDQCLESNDNSDGV 891

  Fly   758 VKKKKLPKKA------------------------------PPKKVASSE----TDAKRKKKSVQV 788
            |....||.||                              ..|:||||.    .|..:|..||.|
plant   892 VASPALPTKAVKEKILNDSDSGELKDIKTDVKSEADCTSDSTKRVASSMLTECRDVSKKVDSVAV 956

  Fly   789 EESDDEEAKEKEKEKEKPKPPKQLPKKRKTAFTEELIGDYKGILARKRMASLNASAIVAATYEVE 853
            |::..|...:.:||:   |||        ||.:.||:
plant   957 EQTPLEGVDDDKKEE---KPP--------TALSSELV---------------------------- 982

  Fly   854 RHLDKNLASDCSSFESYDELDTMPTTTSKVTSAAAIKTEVIHIKKEPKESKESLRERERERESER 918
                |.:..|            :|     |:|..:...:.:.|.:...|...::.....:::..:
plant   983 ----KKVEED------------VP-----VSSGISRDMDAVSIGRPITEMVNNVAFNHMDQKDVK 1026

  Fly   919 RRERDNELKDSTVGKMSSHSIIEESNDSKYSKETKETNTDTTITTTGYRDSAA----STKDAKDC 979
            :.::|   .|::||.:...|...:|:.:|...|..|.|.:.:.....|....|    |.|:|:|.
plant  1027 KIKQD---CDTSVGAIKDTSAGLDSSVTKGKVEPVEGNLENSEVKERYSGLRATPGLSPKEAEDL 1088

  Fly   980 SRPTSSSVVIVQDTDVTITGVYVNA-----SNGAAQEAYCKMQYRVQSSVTE------------- 1026
            .||....   ..|.|....|...:|     |..||..|..:|..||:..:.|
plant  1089 ERPNGPK---TSDADGDEAGECTSAARDASSVSAAASAGSEMDARVEFDLNEGFDGDDAKHGDSN 1150

  Fly  1027 ----ERVLRPGSVEPPKSYT-PLSALSS---------------MLPP-------GASSGLSEAHS 1064
                ...|.|..::|.|:.. |::.:||               .:||       ||......|.:
plant  1151 NFSGSVFLTPTPLQPVKTLPFPVAPVSSGTRASITVAAAAKGPFVPPEDLLRNKGAVGWRGSAAT 1215

  Fly  1065 SPPLPVHAAPTGPH-VLL-------PGEHLSAGMYHAP----DLGLHTEHALPD----HHGPP-- 1111
            |...|  |.|..|. |||       .....|||.....    ||.:..|..|.|    ..|.|
plant  1216 SAFRP--AEPRKPQDVLLSINNTSTSDASTSAGKQTRTFLDFDLNVPDERVLEDLASQRSGNPTN 1278

  Fly  1112 -----PPSYAAAAAAAAAAAAYHAHQLAPGGGGVLHMH------HQHQYAAHAAHA--HHYQQAA 1163
                 ..|:....:....:|..|:     .||..|.::      ....|..:::|.  ..:||..
plant  1279 CTSDITNSFDQVRSGVMGSALDHS-----SGGLDLDLNKVDDSTDMISYTMNSSHRLDSSFQQVK 1338

  Fly  1164 EYHGGPPPPPHHYGGPPPQGHYGPPPG---------APVPVPVAV-PNTVTVPPERCDVGSPP-- 1216
            .                      |..|         .||....|| |:.|.....|..:.|.|
plant  1339 L----------------------PSTGGRRDFDLNDGPVGDDAAVEPSMVLNQHSRSGLPSQPSL 1381

  Fly  1217 -----------------PSYRASAYPPPSSVGMPP--PTLGGGSSAFCAPSPLHHHQHQHQQPGP 1262
                             |:  |:||   |:|.|||  |..|.      .|.|:...:...:..||
plant  1382 SGIRVNGENMASFSTWFPA--ANAY---SAVSMPPIMPERGD------QPFPMIATRGPQRMLGP 1435

  Fly  1263 GVGPPHHDPSGYYQPAGPLISPHVIAAPPPPAQVKKLQ------EEDGPVSAAGSPTQLQQQQAA 1321
            ..|.....|.||   .||::|    ::|..|.|....|      ....||::|..|
plant  1436 TTGVSSFTPEGY---RGPVLS----SSPAMPFQSTTFQYPVFPFGNSFPVTSANFP--------- 1484

  Fly  1322 AEAAAAAADQAAAQSQSQSQGQS-HGHAHSHAHNPQQAQHPPQPQPYPAGAVAAAAAAAAAHQGV 1385
                    ..:.|...|.|.|:: ....:|....|........|:||..|.....:.......|.
plant  1485 --------GASTAHMDSSSSGRACFPGVNSQILGPGVPVPSNYPRPYIVGLPNGGSNGGVLDNGA 1541

  Fly  1386 PYSRS 1390
            .:.||
plant  1542 KWFRS 1546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hers	NP_608360.2	BAH_BAHCC1	2366..2519	CDD:240065
SUO	NP_190388.2	BAH	46..173	CDD:470629	3/5 (60%)
		TFS2N	332..411	CDD:197766	17/86 (20%)
		TFSII	362..>512	CDD:273592	38/205 (19%)