Protein Alignment Hers and bahd1

DIOPT Version :10

• Sequence 1: NP_608360.2
• Gene: Hers / 33000
• FlyBaseID: FBgn0052529
• Length: 2529
• Species: Drosophila melanogaster
• Sequence 2: XP_012824784.1
• Gene: bahd1 / 100496335
• XenbaseID: XB-GENE-1008672
• Length: 797
• Species: Xenopus tropicalis
• Alignment Length: 1030
• Identity: 233/1030 - (22%)
• Similarity: 341/1030 - (33%)
• Gaps: 362/1030 - (35%)

  Fly  1600 SCSSSMLLSATSNSNIGGGSSSSSSSSS----STTLPACSSATTTTTASALTTSRGPVKNVTPNN 1660
            :|.|.:       |::|.|..|.....:    ....||.:..|.|...:.|....|
 Frog    19 ACQSRI-------SSVGRGILSKDIRKAYPLRRRLSPAMNEKTCTVVLTRLEDVAG--------- 67

  Fly  1661 SNSSGHTSTNSCRSSNNSNNSSNSSCQTIEMTSWATAATNTTSTTATTATTGTQCQMLVKTELKG 1725
                      ||.....|....|.||       |..             ..||         ||.
 Frog    68 ----------SCIMEGQSGAQPNISC-------WVD-------------DFGT---------LKV 93

  Fly  1726 ENPQVTKMQYEAHVMPPPTPPESYCASDEKLLDDQEQE----AELELRLRLGLGLEKSHGGQQHI 1786
            .....:|||   .|.|.........:|.:.:.|..|..    |.|.......|..|:..|
 Frog    94 HTGHSSKMQ---RVTPKGKRYSGVTSSMDNIRDFPEPRKRRLASLNAEAVNNLLFERDDG----- 150

  Fly  1787 EAYDLTCSTPPPVTVPQAAAVPRKAR--IGKSMAREMVYAAQQQLLPEKQLKQPKEAAAKLEAEP 1849
                  ||              ||.|  .||:....:.......|.|...| ..|.:..:..|..
 Frog   151 ------CS--------------RKIRKDFGKASENGISDEGWTNLKPNCHL-HSKRSRQRCMASG 194

  Fly  1850 EMP-FVLKAEIKAETKIKIEHDGEAQASTHISQLPDLKPTIKTEPEQELEQEAASVPSVAKTEPQ 1913
            ::| .|.::|:|.|.|:             :|..|..|             ..||:.:||..:..
 Frog   195 QLPDEVFESEMKVEDKV-------------VSYSPAPK-------------RLASLNAVAFLKLT 233

  Fly  1914 PEVEVEREQQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKTKTNNSYKSLIKQAEPKSYLCPGRR 1978
            .|.:...:|:.....:..:...|.||            .|.|||.|:|.
 Frog   234 SERDHPLKQRSKSDGDTSRSITGCSK------------SKLKTNKSHKK---------------- 270

  Fly  1979 FIRRHGRAPAKYVKRRQMILTQRQQQRMRLQRREQ----QQQRRQQREAAAEVVAGAVVTPSLAG 2039
                      ..||.::.:|.::.:.....|....    :.:.|...:::.:.          .|
 Frog   271 ----------NCVKSKKELLHRKMEDHHGWQEGGDHGILKPEHRNSSKSSGKT----------EG 315

  Fly  2040 NPIEQA-----GSEVSIVKDQAPNSSATPSASPKRARP------RKQE-------IAALH----- 2081
            ..:|::     |||  .:..:.|......|..|:..||      .||:       :..||
 Frog   316 VHVERSSNNYDGSE--SLYHRLPLMGGQASMKPEYGRPGEKSPTPKQDFQQPSFPVQQLHHLPVP 378

  Fly  2082 --------LLEGLDTTLSRG-------------------------YFSDP----ELNHSSRKQAP 2109
                    |....|.|.|.|                         .|..|    ||..|.....|
 Frog   379 GSLTDCVCLCHPSDITSSDGTYISYGQSGLPYSGYCDFSMYPKDELFPQPVPCEELLVSQSSFPP 443

  Fly  2110 TA-VGGL------YAASSPLTTATD----------HRGKQTTAEKRSKSETKKPPSGESSES--- 2154
            :. :|.|      |:......|.||          .|...|..|.:|.| .|||.:.|..:|
 Frog   444 SGMIGHLPWCTSRYSFGEDTGTNTDSLCGLIRLPISRVTNTHMEHKSYS-FKKPFTAEGYKSHDQ 507

  Fly  2155 ---GLPCKKPRKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADL 2216
               .:|.......||..:        .|....::...||         ...|.:|.|:|.||..:
 Frog   508 LSLSIPTAGHPVSPAHPL--------LGCPVPSVPPAAE---------PVPNLQTPNSEPQTMAM 555

  Fly  2217 QAQKFREC------PAVTDAKVAGTATSTSTASQQQNQQHSDEQHQFLVPSQPATASATAALAAT 2275
             .:..|||      |:.:.:.|..|:.....:|.:.::.||.       |.|
 Frog   556 -LKTARECPQSSKPPSGSKSGVRNTSGCFHASSNKASKSHSH-------PKQ------------- 599

  Fly  2276 PPPSRQGQATHTKRTRSRCKFGNRKRQRHRPGGVSYELDVTQPPATKANVVPKWNNGWMWAGKAF 2340
                   |..|.:|:                                       .||||..|.|.
 Frog   600 -------QRIHRRRS---------------------------------------TNGWMPVGAAC 618

  Fly  2341 QGAVFLNSDDPLVLRTCYPAMRHVEGDIIRIRDCVLLKAN-EDNELPYVAKVAHLWQNPEDGEMM 2404
            :.||::.::....||..|.|:.. .|:|||:||.||||:. ....:|||||::.||:.|:.||:|
 Frog   619 EKAVYVVNEPEPALRRSYQAVER-NGEIIRVRDTVLLKSGPRKKSMPYVAKISALWEEPKTGELM 682

  Fly  2405 MSLLWYYRPEHTDQGRQRNDCPDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDV 2469
            |||.||||||||..||..:....|::||||:|.||:||:|:|||||||:||||:...::...|.
 Frog   683 MSLFWYYRPEHTQGGRNPSMHQKEIFASRHQDENSIACIEEKCYVLTFAEYCRFCALVKRRGEG- 746

  Fly  2470 EDVSIVPRRPSIATAPGFPV-----RTVPEHTNPELVMFCRRAYEFRTRRLLKLP 2519
                 .|.|.::...|....     |.||:.|:||||..||..|:||..|:||.|
 Frog   747 -----CPNRKALIVPPSAEYSTPSHRRVPDSTDPELVFLCRHVYDFRHGRILKNP 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hers	NP_608360.2	BAH_BAHCC1	2366..2519	CDD:240065	76/158 (48%)
bahd1	XP_012824784.1	BAH_BAHCC1	643..750	CDD:240065	58/112 (52%)