DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNAJB2 and CG3061

DIOPT Version :9

Sequence 1:	NP_006727.2	Gene:	DNAJB2 / 3300	HGNCID:	5228	Length:	324	Species:	Homo sapiens
Sequence 2:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	124	Identity:	47/124 - (37%)
Similarity:	62/124 - (50%)	Gaps:	24/124 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     4 YYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRY 68
            |||:|.|.::|:..:|||||::.|||.|||||  ....|.:.||.:..|..||:|..||:.||.|
  Fly   107 YYEVLGVSKTATDSEIKKAYKKLALQLHPDKN--KAPGAVEAFKALGNAAGVLTDAEKRKNYDLY 169

Human    69 G-REGLTGTGTGPSRAEAGSGGP-----------GFTFTFR---SPEEVFREFFGSGDP 112
            | .|...|.|.       ..||.           |::..|:   |.||:|..||..|.|
  Fly   170 GINESHNGHGN-------NGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFNGGFP 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	45/120 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..90		4/19 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..324
		CAAX motif. /evidence=ECO:0000269\|PubMed:12754272	321..324
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	47/124 (38%)
		DnaJ	106..167	CDD:278647	28/61 (46%)
		DUF1977	269..366	CDD:286411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740