DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNAJB2 and CG12020

DIOPT Version :9

Sequence 1:	NP_006727.2	Gene:	DNAJB2 / 3300	HGNCID:	5228	Length:	324	Species:	Homo sapiens
Sequence 2:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	138	Identity:	40/138 - (28%)
Similarity:	58/138 - (42%)	Gaps:	35/138 - (25%)

- Green bases have known domain annotations that are detailed below.

Human     4 YYEILDVPRSASADDIKKAYRRKALQW--HPDKNPDNKEFA----------------EKKFKEVA 50
            ||.:||.||.|:.:.|..||||.|::.  |.||. |.::|.                .:::..|.
  Fly     8 YYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKK-DEQDFVPLAQEGRLTHLSPMGEPRQWAYVN 71

Human    51 EAYEVLSDKHKREIYDRYGREGL-----TGTGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSG 110
            .|::||.:...|.||||:|..||     ...|..|.....|           ...:|:...|||.
  Fly    72 MAFDVLGNDLYRAIYDRFGEAGLFEGVMLPNGYFPPYQYDG-----------DHMKVYERVFGSY 125

Human   111 DPFAELFD 118
            .|:|.:.|
  Fly   126 SPYANVID 133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	36/128 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..90		5/24 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..324
		CAAX motif. /evidence=ECO:0000269\|PubMed:12754272	321..324
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	40/138 (29%)
		DnaJ	7..87	CDD:278647	24/79 (30%)
		DnaJ_C	156..335	CDD:199909
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810