Protein Alignment SkpE and SKP1

DIOPT Version :9

• Sequence 1: NP_608359.1
• Gene: SkpE / 32997
• FlyBaseID: FBgn0031074
• Length: 167
• Species: Drosophila melanogaster
• Sequence 2: NP_733779.1
• Gene: SKP1 / 6500
• HGNCID: 10899
• Length: 163
• Species: Homo sapiens
• Alignment Length: 154
• Identity: 72/154 - (46%)
• Similarity: 98/154 - (63%)
• Gaps: 2/154 - (1%)

  Fly     4 PTIKLESSEGVIFPTEVRVAMVSETIKTMLDHFAVQND-ENAIVPLHSVSTFTLGKILAWANHHK 67
            |:|||:||:|.||..:|.:|..|.||||||:...:.:: ::..|||.:|:...|.|::.|..|||
Human     2 PSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHK 66

  Fly    68 DDDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGK 132
             ||....|.:|.|.:|...|..||..||.|:..||.|:||||..|.|||||::|...|||||:||
Human    67 -DDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   133 TPEEIRFIFNIPEDVSPSVDGELR 156
            ||||||..|||..|.:...:.::|
Human   131 TPEEIRKTFNIKNDFTEEEEAQVR 154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SkpE	NP_608359.1	SKP1	3..156	CDD:227528	71/152 (47%)
		BTB	6..114	CDD:295341	47/108 (44%)
		Skp1	88..156	CDD:279768	36/67 (54%)
SKP1	NP_733779.1	BTB_POZ_SKP1	4..127	CDD:349631	56/123 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..83		9/20 (45%)
		Interaction with the F-box domain of F-box proteins. /evidence=ECO:0000250	104..163		29/51 (57%)
		Skp1	113..160	CDD:396171	23/42 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.820