DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpE and skp1

DIOPT Version :9

Sequence 1:	NP_608359.1	Gene:	SkpE / 32997	FlyBaseID:	FBgn0031074	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_001016519.1	Gene:	skp1 / 549273	XenbaseID:	XB-GENE-919631	Length:	163	Species:	Xenopus tropicalis

Alignment Length:	154	Identity:	72/154 - (46%)
Similarity:	98/154 - (63%)	Gaps:	2/154 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PTIKLESSEGVIFPTEVRVAMVSETIKTMLDHFAVQND-ENAIVPLHSVSTFTLGKILAWANHHK 67
            |:|||:||:|.||..:|.:|..|.||||||:...:.:: ::..|||.:|:...|.|::.|..|||
Frog     2 PSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHK 66

  Fly    68 DDDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGK 132
             ||....|.:|.|.:|...|..||..||.|:..||.|:||||..|.|||||::|...|||||:||
Frog    67 -DDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   133 TPEEIRFIFNIPEDVSPSVDGELR 156
            ||||||..|||..|.:...:.::|
Frog   131 TPEEIRKTFNIKNDFTEEEEAQVR 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpE	NP_608359.1	SKP1	3..156	CDD:227528	71/152 (47%)
		BTB	6..114	CDD:295341	47/108 (44%)
		Skp1	88..156	CDD:279768	36/67 (54%)
skp1	NP_001016519.1	BTB_POZ_SKP1	4..127	CDD:349631	56/123 (46%)
skp1	NP_001016519.1	Skp1	113..160	CDD:396171	23/42 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110