DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpE and SkpB

DIOPT Version :9

Sequence 1:	NP_608359.1	Gene:	SkpE / 32997	FlyBaseID:	FBgn0031074	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_610729.1	Gene:	SkpB / 36298	FlyBaseID:	FBgn0026176	Length:	161	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	68/153 - (44%)
Similarity:	98/153 - (64%)	Gaps:	2/153 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PTIKLESSEGVIFPTEVRVAMVSETIKTMLDHFAVQNDENAIVPLHSVSTFTLGKILAWANHHKD 68
            |.|:|||::..||.|:..:|..||||:..::....::| |:::||.:|::..|.|:|.||.:||
  Fly     2 PIIRLESADKEIFDTDQEIAKCSETIRIAIEDLGDESD-NSVLPLPNVNSLILKKVLHWATYHK- 64

  Fly    69 DDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGKT 133
            ||...||..|.|.:|...||.|||.||.|:..||.|:||||..|.|:|||::|...|||||:||:
  Fly    65 DDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGKS 129

  Fly   134 PEEIRFIFNIPEDVSPSVDGELR 156
            |:.||..|.|..|..|..:.::|
  Fly   130 PQAIRDTFAIQNDFLPQEEEQVR 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpE	NP_608359.1	SKP1	3..156	CDD:227528	67/151 (44%)
		BTB	6..114	CDD:295341	47/107 (44%)
		Skp1	88..156	CDD:279768	34/67 (51%)
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	68/153 (44%)
		Skp1	1..110	CDD:214704	48/109 (44%)
		Skp1	84..158	CDD:279768	35/69 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452340
Domainoid	1	1.000	51	1.000	Domainoid score	I4316
eggNOG	1	0.900	-	-		E1_COG5201
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.800