DRSC/TRiP Functional Genomics Resources

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Protein Alignment SkpE and Skp1

DIOPT Version :9

Sequence 1:NP_608359.1 Gene:SkpE / 32997 FlyBaseID:FBgn0031074 Length:167 Species:Drosophila melanogaster
Sequence 2:NP_035673.3 Gene:Skp1 / 21402 MGIID:103575 Length:163 Species:Mus musculus


Alignment Length:154 Identity:73/154 - (47%)
Similarity:98/154 - (63%) Gaps:2/154 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 PTIKLESSEGVIFPTEVRVAMVSETIKTMLDHFAVQND-ENAIVPLHSVSTFTLGKILAWANHHK 67
            |||||:||:|.||..:|.:|..|.||||||:...:.:: ::..|||.:|:...|.|::.|..|||
Mouse     2 PTIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHK 66

  Fly    68 DDDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGK 132
             ||....|.:|.|.:|...|..||..||.|:..||.|:||||..|.|||||::|...|||||:||
Mouse    67 -DDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   133 TPEEIRFIFNIPEDVSPSVDGELR 156
            ||||||..|||..|.:...:.::|
Mouse   131 TPEEIRKTFNIKNDFTEEEEAQVR 154

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SkpENP_608359.1 SKP1 3..156 CDD:227528 72/152 (47%)
BTB 6..114 CDD:295341 47/108 (44%)
Skp1 88..156 CDD:279768 36/67 (54%)
Skp1NP_035673.3 BTB_POZ_SKP1 3..127 CDD:349631 57/124 (46%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..83 9/20 (45%)
Interaction with the F-box domain of F-box proteins. /evidence=ECO:0000250 104..163 29/51 (57%)
Skp1 113..160 CDD:396171 23/42 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839320
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5201
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S272
OMA 1 1.010 - - QHG54148
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000367
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11165
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
87.760

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