DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SkpE and skr-20

DIOPT Version :9

Sequence 1:	NP_608359.1	Gene:	SkpE / 32997	FlyBaseID:	FBgn0031074	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_510192.1	Gene:	skr-20 / 181445	WormBaseID:	WBGene00004826	Length:	173	Species:	Caenorhabditis elegans

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	70/153 - (45%)	Gaps:	22/153 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PTIKLESSEGVIFPTE----VRVAMVSETIKTMLDHFAVQNDENA------IVPLHSVSTFTLGK 58
            |..||:|.:|.||..|    ...|.:::   ..:||..  ||.|.      :||.||   ..:..
Worm     8 PLYKLKSEDGQIFNVERGPMKFCAFINQ---KFIDHGV--NDRNCERADPILVPFHS---SIVQA 64

  Fly    59 ILAWANHHKDDDDQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYN 123
            ::.|..|::|:.....:.:    .|.:..|.||..|..|.|..|..::.|:..|.::.|:.:...
Worm    65 VIEWLYHYQDNPLARRDSK----IRYHDFSEWDKQFFNVESGVLFALLNASHALGVEDLMNMGCA 125

  Fly   124 VVANMIRGKTPEEIRFIFNIPED 146
            ..|.:||||:.||||.|:.|..|
Worm   126 AAAELIRGKSTEEIRKIYGIRSD 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpE	NP_608359.1	SKP1	3..156	CDD:227528	44/153 (29%)
		BTB	6..114	CDD:295341	30/117 (26%)
		Skp1	88..156	CDD:279768	22/59 (37%)
skr-20	NP_510192.1	Skp1	7..116	CDD:214704	31/119 (26%)
skr-20	NP_510192.1	Skp1	90..154	CDD:279768	22/59 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850