DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpE and skr-5

DIOPT Version :9

Sequence 1:	NP_608359.1	Gene:	SkpE / 32997	FlyBaseID:	FBgn0031074	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_507393.1	Gene:	skr-5 / 180148	WormBaseID:	WBGene00004811	Length:	145	Species:	Caenorhabditis elegans

Alignment Length:	143	Identity:	51/143 - (35%)
Similarity:	79/143 - (55%)	Gaps:	7/143 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IKLESSEGVIFPTEVRVAMVSETIKTMLDHFAVQNDENAIVPLHSVSTFTLGKILAWANHHKDDD 70
            :|:.:|:.|.|....::|..|:    :|..|.|.|....| ||.:|::....|::.|..:|.:|.
Worm     8 VKIVTSDDVEFIVSPKIANQSK----LLADFVVLNQREPI-PLKNVTSEIFKKVIEWCEYHAEDI 67

  Fly    71 DQSTEGEELKPRRPYAISPWDAIFLMVNSTTLLEIILAAKQLQIKGLLELTYNVVANMIRGKTPE 135
            .:..:..|.|  |...|..||..||.|:..||.|::|||..|.||||..:|...:||.|:||:||
Worm    68 PKPPDNVEEK--RTDDIGEWDVEFLKVDKGTLFELVLAATYLDIKGLFNVTCKSIANSIKGKSPE 130

  Fly   136 EIRFIFNIPEDVS 148
            |||.:||:..:.:
Worm   131 EIRAVFNLGNETN 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpE	NP_608359.1	SKP1	3..156	CDD:227528	51/143 (36%)
		BTB	6..114	CDD:295341	34/107 (32%)
		Skp1	88..156	CDD:279768	29/61 (48%)
skr-5	NP_507393.1	Skp1	5..109	CDD:214704	34/107 (32%)
skr-5	NP_507393.1	Skp1	84..>141	CDD:279768	29/56 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160616
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.770