DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpC and skr-7

DIOPT Version :9

Sequence 1:	NP_608358.1	Gene:	SkpC / 32996	FlyBaseID:	FBgn0026175	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_504221.1	Gene:	skr-7 / 178840	WormBaseID:	WBGene00004813	Length:	194	Species:	Caenorhabditis elegans

Alignment Length:	171	Identity:	56/171 - (32%)
Similarity:	90/171 - (52%)	Gaps:	31/171 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DAPTI-----KLESSDGMIFSTEVRAAKLSETIKTMLEVSAVENDENAIVPLP--KVNAFILSKI 59
            :||.:     |:|||||.::.....|.|.|.|:..::. :.|.||..::.|:|  .|...|:..:
Worm    14 EAPIVAPIMYKVESSDGQVYEISDEAVKQSNTLSNLIS-TCVANDVASMDPIPITNVTGNIMKMV 77

  Fly    60 LTWIYHHK------DDDAHGAEGVELSPQSPHDISA--WDANFINVDQPTLFEIILAANYLEIKG 116
            :.|...||      :||:           .|.:|:.  ||.||:.:|...||::|:|:|:|::.|
Worm    78 IEWCEKHKGETLPVEDDS-----------VPKNITVPEWDTNFLKIDNDVLFDLIVASNFLDVPG 131

  Fly   117 LVDLCCKTVANMIRGKTPEEIRHTFNIP----DEIPSRTAQ 153
            |:...||.||||..||:|:|:|..|.||    ||...:.|:
Worm   132 LMSYACKMVANMAIGKSPDEMRVLFAIPTDEEDEAAEKAAK 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpC	NP_608358.1	Skp1	6..114	CDD:214704	35/122 (29%)
SkpC	NP_608358.1	Skp1	88..>146	CDD:279768	27/63 (43%)
skr-7	NP_504221.1	Skp1	20..129	CDD:214704	35/120 (29%)
skr-7	NP_504221.1	Skp1	103..>160	CDD:279768	26/56 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810