DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpD and skr-2

DIOPT Version :9

Sequence 1:	NP_608357.2	Gene:	SkpD / 32995	FlyBaseID:	FBgn0026174	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_492512.1	Gene:	skr-2 / 172773	WormBaseID:	WBGene00004808	Length:	174	Species:	Caenorhabditis elegans

Alignment Length:	156	Identity:	67/156 - (42%)
Similarity:	97/156 - (62%)	Gaps:	9/156 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IKLESSDGVIFSTEVKAAKLSETIKTMLEVSAVENDE--NA-VVPLPKVNAFILNKILTWAYHHK 67
            ||:.|||..||.......:||.|:.|:|....:::||  || .:|:..|.|.||.|::.|...|:
Worm    16 IKISSSDDEIFLVPRNVIRLSNTLNTLLVDLGLDDDEGTNAEPIPVQNVTASILKKVINWCTKHQ 80

  Fly    68 DDDDQAAEGEELTPQSPHDISPWDANFINVDQPILFEITVAANYLEIKGLEDLCCKTLANMIRGK 132
            .|.....:.|:.|..|   |..||..|:::||..|||:.:|||||:||||.|:.|:::||||:||
Worm    81 SDPIPTEDSEKKTDGS---IQDWDKKFLDIDQGTLFELILAANYLDIKGLLDVACQSVANMIKGK 142

  Fly   133 TPEEIRQTFNIEDDLPIDTAELGEDL 158
            :|:|||:.|||:||.   |||..|.:
Worm   143 SPDEIRRAFNIKDDF---TAEEREQI 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpD	NP_608357.2	Skp1	6..114	CDD:214704	42/110 (38%)
SkpD	NP_608357.2	Skp1	88..>147	CDD:279768	33/58 (57%)
skr-2	NP_492512.1	SKP1	16..174	CDD:227528	67/156 (43%)
		Skp1	16..124	CDD:214704	42/110 (38%)
		Skp1	99..172	CDD:279768	38/70 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160671
Domainoid	1	1.000	56	1.000	Domainoid score	I7318
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X346
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.770