DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zld and Kah

DIOPT Version :9

Sequence 1:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster
Sequence 2:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	75/337 - (22%)
Similarity:	127/337 - (37%)	Gaps:	76/337 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1222 TVSSSRATPALEMDMATLMQHHQDYEMEQYQMQHQQLDQMQQHQQQLDHQQQQQILADQTQTMAQ 1286
            |:|.|.:..:......:..|..:|:.            .:|.|.....|..:|..:.:.|..:..
  Fly    65 TISDSNSCASSSSSSTSSRQSSEDHL------------GLQGHSSVHHHHGEQGEILNSTSLLED 117

  Fly  1287 QPLAKKRRGGNATPSTTKRRRNSSVGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSG 1351
            :.:..:.....:|.|...|.|.:       |.:.:......|..|:|.:......:.|.::.:.|
  Fly   118 EHICPECGKKYSTSSNLARHRQT-------HRSIMDKKARHCPYCEKVYVSMPAYSMHVRTHNQG 175

  Fly  1352 EYPFRCQKCGKRFQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCD 1416
               ..||.|||||....:...|:..| |.:||.||.:|.|.|..|::||.|::. |:..|.|.|.
  Fly   176 ---CECQFCGKRFSRPWLLQGHIRTH-TGEKPFKCGVCEKAFADKSNLRAHIQT-HSNTKPHTCA 235

  Fly  1417 ICEKGFCRKDHLRKHLET---HNRPRVVGKKSAAAAAAAAAAAAVTATAGLGGAPAAGSIKAAFA 1478
            .|.|.|..|.:|.||.|:   .||..|.|..:|:.                ...|::...:.|..
  Fly   236 RCGKAFALKSYLYKHEESSCMKNRGGVPGSGAASG----------------NRPPSSPKRQQAEV 284

  Fly  1479 RSLTVTAVSSEPGAGVAIPSAPATATCAPVSVSASALVQAVNPSLTSGLSLKRHIDDVAVDDDSL 1543
            .|.|::|::         |.:||.|.||....:.|.|.                        :.|
  Fly   285 TSGTISALA---------PGSPAAAVCAASDSAKSTLA------------------------NKL 316

  Fly  1544 LEEDEDEMEMEM 1555
            |::::|..:..|
  Fly   317 LQKEKDRRQAAM 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	19/60 (32%)
		C2H2 Zn finger	1328..1349	CDD:275368	4/20 (20%)
		C2H2 Zn finger	1357..1377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1386..1407	CDD:275368	8/20 (40%)
		zf-H2C2_2	1398..1422	CDD:290200	9/23 (39%)
		zf-C2H2	1413..1435	CDD:278523	10/24 (42%)
		C2H2 Zn finger	1415..1435	CDD:275368	9/22 (41%)
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	4/28 (14%)
		C2H2 Zn finger	121..141	CDD:275368	4/26 (15%)
		zf-C2H2	176..198	CDD:278523	8/21 (38%)
		C2H2 Zn finger	178..198	CDD:275368	8/19 (42%)
		zf-H2C2_2	191..214	CDD:290200	9/23 (39%)
		zf-C2H2	204..226	CDD:278523	9/22 (41%)
		C2H2 Zn finger	206..226	CDD:275368	8/20 (40%)
		zf-H2C2_2	218..242	CDD:290200	9/24 (38%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457090
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930