DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zld and CG11906

DIOPT Version :9

Sequence 1:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster
Sequence 2:	NP_611402.2	Gene:	CG11906 / 37209	FlyBaseID:	FBgn0034425	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	88/514 - (17%)
Similarity:	146/514 - (28%)	Gaps:	207/514 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly  1205 QEAQTPTLTVLSTPYSPTVSSSRATPALEMDMATLMQHHQDYEMEQYQMQHQQ------------ 1257
            |:|..|         .|..||:....::|.|      :.||.:......:.:.
  Fly     2 QDATAP---------DPEPSSTNGNCSVEHD------NRQDQDENHVGAEREAEANDANCTVCGA 51

  Fly  1258 ------LDQMQQHQQQLDHQQQQQILAD----------------------QTQTMAQQPLAKKRR 1294
                  ||....|..|....:..:|.||                      .|:::.|:....:|.
  Fly    52 AKASALLDLRSNHVMQRRLSRDWKIHADVIRSTLKAICVECVCKLNMHSEVTRSLMQRMQRLQRS 116

  Fly  1295 GGNATPSTTKRRRNSSVGSTSPHSTTLPSGRIK--CLECDKEFT---------KNC-----YLTQ 1343
            ||..|..||      :..|.|.||..:....:.  .:|..:|..         .:|     ||.|
  Fly   117 GGETTKVTT------TTTSPSQHSPPIADAEVSTTLIESQEEVAHSGQSVRSRSSCSVLEVYLAQ 175

  Fly  1344 --------HNKSFHSGEYPFR----CQKCGKRFQSEDVYTTHLGR----HRTQDKPHK------- 1385
                    ..:..|:..:.:|    |.:||:.:...|.|..||.|    .|.|.:|.:
  Fly   176 QPYSPSAKETEEKHAEGWKWRTRLECHECGRAYFRRDYYAQHLRRCSKTRRKQPRPSRVKCRVLN 240

  Fly  1386 --------------------CELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRK 1430
                                |..|..:|......|:|....|.  :::.||:||.....|.....
  Fly   241 EASYDEEAPSRAIRSSRIYYCRHCDAEFETLISKRQHERMKHQ--QRYPCDLCEAQLDTKYEWEM 303

  Fly  1431 HLETHNRPRVVGKKSAAAAAAAAAAAAVTATAGLGGAPAAGSIKAAFARSLTVTAVSSEPGAGVA 1495
            |   |.   :...|..|                                    .|:..:..||..
  Fly   304 H---HT---ICQAKQEA------------------------------------LAIVEQQEAGQT 326

  Fly  1496 IPSAPATATCAPVSVSASALVQAVNPSLTSGLSLKRHIDDVAVDDDSLLEEDEDEMEMEMEMDML 1560
            :.::.....|:..|.|.:.                    ..|.|...:.||:|||.:.|:|....
  Fly   327 VMTSRVPRACSMRSRSRAC--------------------SEAWDRYDMDEEEEDEEDEEIESGGE 371

  Fly  1561 EEEDEEEEELGDHHMIIKSEYVQE-----------------EFQMIE------KSIELY 1596
            |.|:.||:.:....|....:::..                 ::.|:|      |..:||
  Fly   372 ELEEGEEDAMYARRMNFTGDWIVNHSRSNSNSAGNLSLLYGDYGMVETHMTTDKEYDLY 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	20/117 (17%)
		C2H2 Zn finger	1328..1349	CDD:275368	6/42 (14%)
		C2H2 Zn finger	1357..1377	CDD:275368	8/23 (35%)
		C2H2 Zn finger	1386..1407	CDD:275368	5/20 (25%)
		zf-H2C2_2	1398..1422	CDD:290200	7/23 (30%)
		zf-C2H2	1413..1435	CDD:278523	6/21 (29%)
		C2H2 Zn finger	1415..1435	CDD:275368	6/19 (32%)
CG11906	NP_611402.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930