DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zld and CG32767

DIOPT Version :9

Sequence 1:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster
Sequence 2:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster

Alignment Length:	1015	Identity:	227/1015 - (22%)
Similarity:	346/1015 - (34%)	Gaps:	358/1015 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   654 PDYGGGGGL----GVGAMGGAAMSQ---YSASPSPTQQ----QQH-HLNHHQQQANGYANGTANG 706
            |..|...|:    |:.|:..:|:||   :....:|.:|    .|| |::||...
  Fly    23 PAVGAAAGVKDMDGLMAINDSALSQQIEFILQDAPMEQDDDPHQHTHVHHHHHS----------- 76

  Fly   707 YGYMQQQVQSTTNASPQHASNNNSNNQQQQQQQQQHHQQQMPQHHNSVLNGHPNGLAGPSAPHNN 771
                            ||..:::|:.|||||..||..|||  |||:               ||::
  Fly    77 ----------------QHHPHSHSHQQQQQQHLQQQQQQQ--QHHH---------------PHHH 108

  Fly   772 NTTQMPSSQMRGLLNETTTTPPPTTTTRAPQITTTATTTTTAATTVAIKSEQMEDSNHTHTHTHT 836
            ..           |:.::...|||....|..:...|||..|||...
  Fly   109 LK-----------LDNSSNNHPPTAAAAAAAVAVAATTAATAAAAT------------------- 143

  Fly   837 HPNHSHSQDRSHSSSSSSSMATEEAEEQELRDQEQADDHLHQHQQASQQYLLSARHYHSSTPNTL 901
              |:|.|.. |:||||:|:.:.....:|:|..|:|        ||..|.:||:.|       ..:
  Fly   144 --NNSASFS-SNSSSSNSNNSNHLDNQQQLLIQQQ--------QQQQQHHLLNGR-------RII 190

  Fly   902 SSSNTNPSTPSSNSPHTIYRQEQQGTDFSRTTPPPQPLPPMGMLPPMAMDYNMLALDMPMPMPTL 966
            ..:..|.|..:::.   |..::::..|                  |...|.|:..::
  Fly   191 IQATGNSSVLAASD---IKEEDEEEED------------------PELNDENLQDIE-------- 226

  Fly   967 MHSNMLQCSSTSTTP-----LATTITTSMPDTMQPPQQQLVHHYQAVLHPLHQQLGEQHQRQEAD 1026
               ...|.:.....|     |:|.:...:.:..:.|.                   |:.:..|.|
  Fly   227 ---EEAQAAEADEEPETTAHLSTQVKLELEEDDEMPD-------------------EEEEEDEDD 269

  Fly  1027 HHQQQRELHQLDQQQQQQQALILADSLPHSSSSPTSSSPPPTMPMPLTTITA----PQLLPLQPP 1087
                       |::.|..|       |.:..|:.|.::...|........||    .||:.|  |
  Fly   270 -----------DEELQHGQ-------LEYQISAATQTAGAATSSAAGGAATAGGGSQQLVQL--P 314

  Fly  1088 PPHITSTMPMPPTMHMPIMPPPPQCYQQLQPLDPTMSYHTIIGSGPEAHTGTAGGGYSNQITTSD 1152
            ...|.||     |.|...:|.......||| ..|....:.:.|.       |||..|..
  Fly   315 AGSIVST-----TTHRLSVPVTEAALVQLQ-RRPVYISNAVGGL-------TAGATYVR------ 360

  Fly  1153 GQILQLMPTSLFAPYAPLSPYSVAAQRSPQEGDLPPVHTLTTALHAHQQGGQQEAQTPTLTVLST 1217
                  ||.:.....:|::..:|..|.      ||....:   |...||      |||
  Fly   361 ------MPAAAVISRSPMTVLNVVQQA------LPATQLI---LQTQQQ------QTP------- 397

  Fly  1218 PYSPTVSSSRATPALEMDMA-TLMQHHQDYEMEQYQMQHQQLDQMQQHQQQLDHQQQQQILADQT 1281
                      |..|.|..:| .|.|..|..|.:..|.:.||..|.||.|||...|||||..|.|.
  Fly   398 ----------AAAAAEQQLALALEQQRQQQEQQAQQQRQQQQQQEQQRQQQQQQQQQQQQQAQQE 452

  Fly  1282 QTMAQQ-------------PLAKKRRGGNATPSTTKRRRNSSVGST-----SPHSTTLPSGRIKC 1328
            |...||             |:.....|.::|      ..||:..||     :|.:|...:...:|
  Fly   453 QQRQQQQQLQQQQQQQQTHPVKHSASGSSST------NNNSTTNSTNSNNNTPAATATVTTSYQC 511

  Fly  1329 LECDKEFTKNCYLTQHNKSFHSGEY-----------------------PFRCQKCGKRFQSEDVY 1370
            :||.::|........| :|.|:...                       |:.||.||:..:....:
  Fly   512 VECVEKFDSKELFDIH-RSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNF 575

  Fly  1371 TTHLGRHRTQDK---PHKCELCPKQF--------HHK--------------------TDLRRHVE 1404
            ..|:..|..|..   .:|||:|.|:|        |.|                    ..||.| .
  Fly   576 IKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGH-S 639

  Fly  1405 AIHTGLKQHMCDICEKGF-----------------------CRKD-HLRKHLETHNRPRVVGKKS 1445
            .:|:|:|.|.||:|.|||                       |:|. |.:..|:||.:..:..:..
  Fly   640 KLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHMQVHLRDQPG 704

  Fly  1446 AAAAAAAAAAAAVTATAGLGGAPAAGSIKAAFARSLTVTAVSSEPGAGVAIPSAPATATCAPVSV 1510
            ||||||.||.||        .:.|:.|..::.: |.:.::.||..|...|:.:|..|.|.  |.:
  Fly   705 AAAAAATAAGAA--------SSKASNSSNSSNS-SNSSSSNSSSNGVSAAVSAATTTTTI--VKL 758

  Fly  1511 SASALVQAVNPSLTSGLSLKRHIDDVAVDDDSLLEEDEDE 1550
            .....::....|....|...:| ..:.:||.|.|..||::
  Fly   759 EPPHEIERPGTSSNQQLQQSQH-HQMELDDQSGLSGDEED 797

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	18/86 (21%)
		C2H2 Zn finger	1328..1349	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1357..1377	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1386..1407	CDD:275368	10/48 (21%)
		zf-H2C2_2	1398..1422	CDD:290200	11/23 (48%)
		zf-C2H2	1413..1435	CDD:278523	11/45 (24%)
		C2H2 Zn finger	1415..1435	CDD:275368	10/43 (23%)
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	0/19 (0%)
		C2H2 Zn finger	562..582	CDD:275368	5/19 (26%)
		C2H2 Zn finger	594..614	CDD:275368	7/19 (37%)
		C2H2 Zn finger	622..642	CDD:275368	3/20 (15%)
		zf-C2H2	648..670	CDD:278523	7/21 (33%)
		C2H2 Zn finger	650..670	CDD:275368	6/19 (32%)
		zf-H2C2_2	662..684	CDD:290200	1/21 (5%)
		C2H2 Zn finger	678..698	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100