DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zld and lsy-2

DIOPT Version :9

Sequence 1:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster
Sequence 2:	NP_001024696.1	Gene:	lsy-2 / 180522	WormBaseID:	WBGene00003087	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	53/217 - (24%)
Similarity:	71/217 - (32%)	Gaps:	93/217 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly  1234 MDMATLMQHHQDYEMEQYQMQHQQLDQMQQHQQQLDHQQQQQILADQTQTMAQQPLAKKRRGGNA 1298
            ||.:.:|...|||  .||||...:.|:|.:                                |..
Worm    42 MDDSEMMMDEQDY--SQYQMGFPEEDEMVE--------------------------------GMM 72

  Fly  1299 TPSTTKRRRNSSVGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKR 1363
            ||                                             ::.|      :|..|.|.
Worm    73 TP---------------------------------------------RAVH------QCNVCNKI 86

  Fly  1364 FQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCR-KDH 1427
            |.|......|...| |..||.:|::|.|.|..|::|..| .::|||...|.|..|.| .|| |.:
Worm    87 FVSYKGLQQHAVIH-TDQKPFRCDICSKSFRFKSNLFEH-RSVHTGFTPHACPYCGK-TCRLKGN 148

  Fly  1428 LRKHLETHNRPRVVGKKSAAAA 1449
            |:|||.||    |..|:...||
Worm   149 LKKHLRTH----VTTKEELEAA 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	12/60 (20%)
		C2H2 Zn finger	1328..1349	CDD:275368	0/20 (0%)
		C2H2 Zn finger	1357..1377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1386..1407	CDD:275368	7/20 (35%)
		zf-H2C2_2	1398..1422	CDD:290200	9/23 (39%)
		zf-C2H2	1413..1435	CDD:278523	11/22 (50%)
		C2H2 Zn finger	1415..1435	CDD:275368	10/20 (50%)
lsy-2	NP_001024696.1	zf-C2H2	106..128	CDD:278523	7/22 (32%)
		C2H2 Zn finger	108..128	CDD:275368	7/20 (35%)
		zf-C2H2	134..156	CDD:278523	11/22 (50%)
		C2H2 Zn finger	136..156	CDD:275368	10/20 (50%)
		C2H2 Zn finger	80..100	CDD:275368	6/19 (32%)
		zf-H2C2_2	93..115	CDD:290200	8/22 (36%)
		COG5048	102..>156	CDD:227381	23/55 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930