DRSC/TRiP Functional Genomics Resources

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Protein Alignment zld and Gfi1b

DIOPT Version :9

Sequence 1:NP_001285466.1 Gene:zld / 32994 FlyBaseID:FBgn0259789 Length:1596 Species:Drosophila melanogaster
Sequence 2:NP_001153878.1 Gene:Gfi1b / 14582 MGIID:1276578 Length:363 Species:Mus musculus


Alignment Length:432 Identity:106/432 - (24%)
Similarity:156/432 - (36%) Gaps:103/432 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1030 QQRELHQLDQQQQQQQALILADSL-----PHS-SSSPTSSSPPPTMPMPLTTITAP------QLL 1082
            :.::.|...|.:.|...|:...::     .|| |:||..|:|.|:..:...||...      |.|
Mouse     8 KSKKAHTYHQPRAQGDELVWPPAVIPVAKEHSQSASPLLSTPLPSQTLDWNTIKQEREMLLNQSL 72

  Fly  1083 PLQPPPPHITSTMPMPPTMHMPIMPPPPQCYQQLQPLDPTMSYHTIIGSGPEAHTGTAGGGYSNQ 1147
            |.....|......|.|.....|:...|| .|:      |:.|:.|:..|...::|.|.       
Mouse    73 PKMASAPEGPLVTPQPQDGESPLSESPP-FYK------PSFSWDTLASSYSHSYTQTP------- 123

  Fly  1148 ITTSDGQILQLMPTSLFAPYAPL--SPYSVAAQRSPQEGDLPPVHTLTTALHAHQQGGQQEAQTP 1210
             :|.....|:.......:|..|.  ||.....:.||   .:...|.:...               
Mouse   124 -STMQSAFLERSVRLYGSPLVPSTESPLDFRLRYSP---GMDTYHCVKCN--------------- 169

  Fly  1211 TLTVLSTPYSPTVSSSRA---TPALEMDMATLMQHHQDYEMEQYQMQHQQLDQMQQHQQQLDHQQ 1272
              .|.|||:...|...|:   |.....|:......|              ...::||    .|..
Mouse   170 --KVFSTPHGLEVHVRRSHSGTRPFACDVCGKTFGH--------------AVSLEQH----THVH 214

  Fly  1273 QQQILADQTQTMAQQPLAKKRRGGNATPSTTKRRRNSSVGSTSPHSTTLPSGR-------IKCLE 1330
            .|.:.|                |.:.||:.      :..|..:|.:...|..|       .:|..
Mouse   215 SQGVPA----------------GSSPTPTL------AVPGLEAPPAPDPPGPRFLRQERSFECRM 257

  Fly  1331 CDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKRFQSEDVYTTHLGRHRTQDKPHKCELCPKQFHH 1395
            |.|.|.::..|:.| ...||...|:.||.|||||..:.....|...| |.:|||||::|.|.|..
Mouse   258 CGKAFKRSSTLSTH-LLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIH-TGEKPHKCQVCGKAFSQ 320

  Fly  1396 KTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLET-HN 1436
            .::|..|... |||.|...|::|.|||.||..||:|.|: ||
Mouse   321 SSNLITHSRK-HTGFKPFSCELCTKGFQRKVDLRRHRESQHN 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zldNP_001285466.1 zf-C2H2_jaz 552..577 CDD:288983
LIM 1328..1389 CDD:259829 24/60 (40%)
C2H2 Zn finger 1328..1349 CDD:275368 6/20 (30%)
C2H2 Zn finger 1357..1377 CDD:275368 8/19 (42%)
C2H2 Zn finger 1386..1407 CDD:275368 6/20 (30%)
zf-H2C2_2 1398..1422 CDD:290200 9/23 (39%)
zf-C2H2 1413..1435 CDD:278523 11/22 (50%)
C2H2 Zn finger 1415..1435 CDD:275368 11/20 (55%)
Gfi1bNP_001153878.1 C2H2 Zn finger 165..186 CDD:275368 6/37 (16%)
C2H2 Zn finger 194..214 CDD:275368 5/37 (14%)
zf-C2H2 253..275 CDD:278523 6/22 (27%)
C2H2 Zn finger 255..275 CDD:275368 6/20 (30%)
COG5048 263..>340 CDD:227381 29/79 (37%)
C2H2 Zn finger 283..303 CDD:275368 8/19 (42%)
zf-H2C2_2 295..320 CDD:290200 11/25 (44%)
C2H2 Zn finger 311..331 CDD:275368 6/20 (30%)
C2H2 Zn finger 339..356 CDD:275368 9/16 (56%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24393
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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