DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zld and gfi1b

DIOPT Version :9

Sequence 1:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster
Sequence 2:	XP_002936223.1	Gene:	gfi1b / 100489910	XenbaseID:	XB-GENE-944426	Length:	343	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	89/314 - (28%)
Similarity:	124/314 - (39%)	Gaps:	65/314 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1156 LQLMPTSLFAPYA--PLSPYSVAAQRSPQEGDLPPVHT--LTTALHAHQQGGQQEAQTPTLT--- 1213
            |.|:.||.:|..|  |:.|.:.:..|:.:      |||  .||........|....:.|.::
Frog    29 LDLLATSYYAHCAEFPVEPPAFSTDRNDK------VHTPENTTTEETDIDPGDSREKIPFISRSI 87

  Fly  1214 --------VLST-----PYSPTVSSSRATPALEMDMATLMQHHQDYEMEQYQMQ-HQQLDQ---- 1260
                    .||:     ||.|:..|  |..|......||   |..|..:|...| |..:.|
Frog    88 SPNAFQGIALSSMRPSKPYDPSPLS--AFYAQNFSWETL---HSTYGFKQIPSQIHPSMLQNSIN 147

  Fly  1261 MQQHQQQLDHQQQQQILADQTQTMAQQPLAKKRRGGNATPSTTKRRRNSSVGSTS---------P 1316
            :......||......|    ..:|:..|   |....:..       :.|.|.|||         .
Frog   148 LYSCPPTLDSDSDHPI----NYSMSYSP---KMDSYHCV-------KCSKVFSTSHGLEVHVRRS 198

  Fly  1317 HSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKRFQSEDVYTTHLGRHRTQD 1381
            ||.|.|   ..|..|.|.|.....|.|| .:.||.|..|.|:.|||.|:.....:|||..| :..
Frog   199 HSGTRP---FVCNICGKSFGHAVSLEQH-LNVHSQERSFECKMCGKTFKRSSTLSTHLLIH-SDT 258

  Fly  1382 KPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETH 1435
            :|:.|:.|.|:||.|:|:::|. .||||.|.|.|.:|.|.|.:..:|..|...|
Frog   259 RPYPCQFCGKRFHQKSDMKKHT-YIHTGEKPHKCQVCGKAFSQSSNLITHSRKH 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	22/60 (37%)
		C2H2 Zn finger	1328..1349	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1357..1377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1386..1407	CDD:275368	8/20 (40%)
		zf-H2C2_2	1398..1422	CDD:290200	11/23 (48%)
		zf-C2H2	1413..1435	CDD:278523	7/21 (33%)
		C2H2 Zn finger	1415..1435	CDD:275368	6/19 (32%)
gfi1b	XP_002936223.1	COG5048	<76..337	CDD:227381	74/261 (28%)
		C2H2 Zn finger	178..199	CDD:275368	5/27 (19%)
		PHA00733	<204..252	CDD:177301	18/51 (35%)
		C2H2 Zn finger	207..227	CDD:275368	7/20 (35%)
		C2H2 Zn finger	235..255	CDD:275368	8/19 (42%)
		C2H2 Zn finger	263..283	CDD:275368	8/20 (40%)
		zf-H2C2_2	275..300	CDD:372612	12/25 (48%)
		C2H2 Zn finger	291..311	CDD:275368	6/19 (32%)
		C2H2 Zn finger	319..336	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100