Protein Alignment Pmp70 and Abcd2

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_203503.2
• Gene: Abcd2 / 84356
• RGDID: 69244
• Length: 741
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 266/683 - (38%)
• Similarity: 393/683 - (57%)
• Gaps: 52/683 - (7%)

  Fly    17 GVAGMTAALWIIAYGK------MSNKKRKPGY-----EDKIQYTIAEKKDK--------KAGKAH 62
            |.|...|.|...||..      :..:.::||:     ||   |..||.:::        |.....
  Rat    18 GAAKRAACLVAAAYALKTLYPILGRRLKQPGHRKAKAED---YPPAENRERLHCTEIICKKPAPG 79

  Fly    63 VNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMI-QNATVVESTIIHMNRTKF 126
            :|:.|||||.:|..||.|...:.|||.|.|.:.|||.|:...|::. .:..:|:|.:....|| |
  Rat    80 LNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRT-F 143

  Fly   127 KTALLKYL-TALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNLDNRIANAD 190
            ...|:|:| .|:|| :.|.:.:::...:|.|.|||.|..|.|..|....||||:.|:|.|:||.|
  Rat   144 IIKLVKWLMIAVPA-TFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPD 207

  Fly   191 QLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRL--TVNLGGKT---PSILMLYLLFAGVFLTR 250
            |.||.||..|.:|...||||::||:||:.:..|.|  |....|.:   |::|...:::|...:.:
  Rat   208 QSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLK 272

  Fly   251 LRRPT-GRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLEFR 314
            ...|. |.|..||...:|..|||:||:|.|.||:|||:|:..|...|...|..|...:...|..|
  Rat   273 ACSPKFGTLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKR 337

  Fly   315 VSMGIIDNIIGKYFASIVGFYAVSIPFFS---------ENHP---LLSGENSGQRLQAYYTYGRM 367
            :...:|:..:.||..|..|...|:||..:         |:.|   ::|     .|.:|:.|...:
  Rat   338 LWYIMIEQFLMKYVWSGCGLIMVAIPIITATGFADGDLEDGPKQAMVS-----DRTEAFTTARNL 397

  Fly   368 LVKLAEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTMV---NGNNLAQNAVGSAS 429
            |...|:||.|::.:.:|::.|||:|||:..:..|..::.:|.|:||:.   ..|:.::..:....
  Rat   398 LASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENNSKSRGGLELPL 462

  Fly   430 SNFGPNKGIMCFEDNIIRFEKVPLVTPNGDVLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGE 494
            |:....||.:...|:.|..|.||::||.|:|:...|:|:|:.|.::|:.||||||||||||||..
  Rat   463 SDTLAIKGTVIDVDHGILCENVPIITPAGEVVASSLNFKVEEGMHLLITGPNGCGKSSLFRILSG 527

  Fly   495 LWPTWGGKVTKPSRGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRLGHSDEDLMHYLDIVQLTY 559
            |||.:.|.:.||....:||:||||||:||:||||:|||.:.|||...|::|.||.|.|..|.|.:
  Rat   528 LWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHEKGYTDRDLEHILHSVHLYH 592

  Fly   560 LEQRENGLDSIEDWIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGI 624
            :.|||.|.|::.||.||||||||||:.|||:|||||::|:|||||||||:|||||::......||
  Rat   593 IVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGI 657

  Fly   625 TLFTVSHRKSLWAHHDYYLQFDGRGSYEFATID 657
            :|.:::||.|||.:|.:.|||||.|.:.|..:|
  Rat   658 SLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	264/677 (39%)
		ABC_membrane_2	63..342	CDD:284003	106/286 (37%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	116/204 (57%)
Abcd2	NP_203503.2	Interaction with PEX19. /evidence=ECO:0000250	1..218		70/204 (34%)
		3a01203	74..686	CDD:273360	251/618 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53776
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730