Protein Alignment Pmp70 and abcd4

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001070185.2
• Gene: abcd4 / 767748
• ZFINID: ZDB-GENE-050517-30
• Length: 604
• Species: Danio rerio
• Alignment Length: 620
• Identity: 186/620 - (30%)
• Similarity: 316/620 - (50%)
• Gaps: 62/620 - (10%)

  Fly    67 FFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVES----TIIHMNRTKFK 127
            |.::...:|.||.|. ||.:...:|:   .|:|.::|...:|....::.|    .:...:..|||
Zfish    18 FLQRFYSILKILFPS-WSNQNVRMFM---TLLGVTLSVQLVIYQVGLIPSQFYRVLSERSYGKFK 78

  Fly   128 TALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNLDNRIANADQL 192
            ..::..:..:...|.:.::.::....|.:|:|..||..|:..|..|..||.::.|...|.|.||.
Zfish    79 DLVVFAVVLILINSTLKSLDQYICSLLYVRWRKTLTEDLHHLYFKGRVYYTLNILCKDIDNPDQR 143

  Fly   193 LTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTPSILMLYLLFAGVFLTR-LRRPTG 256
            ::.|:::.|:..:.:.|.:......:..|.|: ..|..|....:.:......|..:.: |..|..
Zfish   144 ISQDVERLCKQMSTMASRLLITPFTVTYYTYQ-CFNSAGWIGFVSIFSYFVVGTIINKILIGPIV 207

  Fly   257 RLTVEEQKLEGEFRYVNSRLITNSEEVAFYQ-GNVR-----EKLTLLASYSKLRSHLRKFLEFRV 315
            .:.||::||||:||:.:.::..|:|..|||: .||.     .||.:|.|..  ||.:.|.|...:
Zfish   208 SMLVEQEKLEGDFRFKHMQIRVNAESAAFYRASNVEHMRTDRKLQMLLSTQ--RSLMNKELWLYL 270

  Fly   316 SMGIIDNIIGKYFASIVGFYAVSIPFFSENHP-LLSGENSGQRLQAYYTYGRML-VKLAEAIGRL 378
            .:...|     |..||:.:..::||.|:.|:. |..||     |.|..:....: :.|.....:|
Zfish   271 GVNTFD-----YMGSILSYIVIAIPIFAGNYDHLTPGE-----LSALISKNAFVCIYLINCFTQL 325

  Fly   379 VLAGREMSRLAGFTARMTELIKVLSDLNK---GTYERTMV-----NGNNLAQNAVGSASSNFGPN 435
            :.....:|.:||:|.|:.||.:.::|:.|   ..|:...|     |.:...|:.  .|.:.|..:
Zfish   326 IDLSTTVSDVAGYTHRIGELQEAMADIAKKQRDEYQYDPVSKAESNSDRELQSV--PADTAFVLD 388

  Fly   436 KGIMCFEDNIIRFEKVPLVTPNGDVLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPTWG 500
            :  :|:        |.||   :.::|:::|:..:..||::||.|..|.||:||.|:|..||....
Zfish   389 R--LCY--------KSPL---SEELLVKDLTLSISQGTHLLVVGNTGTGKTSLLRVLNSLWEPCR 440

  Fly   501 GKVTKPS----RGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRLGH-SDEDLMHYLDIVQLTYL 560
            |.|...:    || |.::||:.|:|.|||||||||| .:|.....|. .||.::.||::|.|:.|
Zfish   441 GSVQMTTCFGPRG-LMFLPQKAYLTDGTLRDQIIYP-LKDIYPSSGSIDDERILKYLELVGLSNL 503

  Fly   561 EQRENGLDS--IEDWIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVG 623
            ..|..|||:  ..:|.||||.||.||:..|||.|.:|:||:|||.|||::.:.||::|:.|::.|
Zfish   504 LTRIGGLDTEVTWNWYDVLSPGEMQRLCFARLLYLQPKFAVLDEATSALTEEAEGQLYNACKQQG 568

  Fly   624 ITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATIDQ 658
            :||.::.||.:|..|||..|:..|.|.:|.:.:.:
Zfish   569 MTLISLGHRSTLEKHHDVMLRLCGGGQWELSKLKE 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	185/613 (30%)
		ABC_membrane_2	63..342	CDD:284003	71/285 (25%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	89/211 (42%)
abcd4	NP_001070185.2	ABC_membrane	14..292	CDD:294371	71/285 (25%)
		YddA	18..603	CDD:226646	186/618 (30%)
		ABCD_peroxisomal_ALDP	385..596	CDD:213190	91/225 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.720