Protein Alignment Pmp70 and Abcd4

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001013118.2
• Gene: Abcd4 / 299196
• RGDID: 1307273
• Length: 606
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 172/619 - (27%)
• Similarity: 300/619 - (48%)
• Gaps: 67/619 - (10%)

  Fly    63 VNSVFFKQLRQLLPILIPGFWSVETGLLF--LVAAALIGRSVSDIWMIQNATVVESTIIHMNRTK 125
            :..|||..            ||.:..|:|  |:..||:.:.|     |....::.|....:...|
  Rat    27 IQKVFFPS------------WSSQNVLMFMTLLCVALLEQLV-----IYQVGLIPSQYYGVLGNK 74

  Fly   126 ----FKTALLKYLTALPAISVVTNVLK----WSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNL 182
                ||.  |.:|..  |:.|:.:.||    ::...|.:.:|.:||.||:..|.....||.::.|
  Rat    75 DLDGFKA--LTFLAV--ALIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHQLYFRARVYYTLNVL 135

  Fly   183 DNRIANADQLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTPSILMLYLLFAGVF 247
            .:.|.|.||.::.|:::||...:.:.|.:......:..|.|:...:.|...|..:..|.:...:.
  Rat   136 RDDIDNPDQRISQDVERFCRQLSSVTSKLIISPFTLAYYTYQCFQSTGWLGPVSIFGYFILGTMV 200

  Fly   248 LTRLRRPTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLE 312
            ...|..|.....|:::||||:||:.:.::..|:|..|||:..:.|.:.......:|....|:.:.
  Rat   201 NKTLMGPIVTKLVQQEKLEGDFRFKHMQIRVNAEPAAFYRAGLVEHMRTDRRLQRLLQTQRELMS 265

  Fly   313 FRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENSGQRLQAYYTYGRML-VKLAEAIG 376
            ..:.:.|..|.. .|..||:.:..::||.|..    :.|:.|...|....:....: :.|.....
  Rat   266 RELWLYIGINTF-DYLGSILSYVVIAIPIFRG----VYGDLSPTELSTLVSKNAFVCIYLISCFT 325

  Fly   377 RLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTMVNGNNLAQNAVGSASSNFGPNKGIMCF 441
            :|:.....:|.:||:|.|:.||.:.|.|:::.:::          ...:|.:..:.....|....
  Rat   326 QLIDLSTTLSDVAGYTHRIGELQEALLDMSRKSHD----------CETLGESEWDLDKAPGWPTT 380

  Fly   442 E--DNIIRFEKVPLVTPNGD-VLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPTWGGKV 503
            |  |.....::|.::.|:.| .|:::||.::..|.::|:.|..|.||:||.|:||.||.:..|.|
  Rat   381 EPSDTAFLLDRVSILAPSSDKPLIKDLSLKICEGQSLLITGNTGTGKTSLLRVLGGLWESMKGSV 445

  Fly   504 TKPS----RGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRL-----GHSDEDLMHYLDIVQLTY 559
            ...:    .|.|| :||:|:.|.||||:|:|||     ::.:     ...||.::.:|::..|:.
  Rat   446 QMLADFGPHGVLF-LPQKPFFTDGTLREQVIYP-----LKEIYPDSGSADDERIVRFLELAGLSS 504

  Fly   560 LEQRENGLDSIED--WIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREV 622
            |..|..|||...|  |.||||.||.||::.|||||.:|::|:|||.|||::.:.|.::|...:::
  Rat   505 LVARTGGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEAESELYRIGQQL 569

  Fly   623 GITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATI 656
            |:|..:|.||.||...|.:.|:..|.||:|...|
  Rat   570 GMTFISVGHRPSLEKFHSWVLRLHGGGSWELTRI 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	170/614 (28%)
		ABC_membrane_2	63..342	CDD:284003	69/288 (24%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	81/216 (38%)
Abcd4	NP_001013118.2	3a01203	9..600	CDD:273360	170/614 (28%)
		ABC_membrane_2	16..294	CDD:284003	69/288 (24%)
		ABCD_peroxisomal_ALDP	387..598	CDD:213190	81/216 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720