Protein Alignment Pmp70 and Abcd4

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_033018.2
• Gene: Abcd4 / 19300
• MGIID: 1349217
• Length: 606
• Species: Mus musculus
• Alignment Length: 624
• Identity: 167/624 - (26%)
• Similarity: 295/624 - (47%)
• Gaps: 77/624 - (12%)

  Fly    63 VNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVESTIIHM------ 121
            :..|||..            ||.:..|:|:....:              |::|..:|:.
Mouse    27 IQKVFFPS------------WSSQNVLMFMTLLCV--------------TLLEQLVIYQVGLIPS 65

  Fly   122 ---------NRTKFKTALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYY 177
                     :...||...|..:|.:...|.:.:..:::...|.:.:|.:||.||:..|.....||
Mouse    66 QYYGVLGNKDLDGFKALTLLAVTLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHHLYFRARVYY 130

  Fly   178 KMSNLDNRIANADQLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTPSILMLYLL 242
            .::.|.:.|.|.||.::.|:::||...:.:.|.:......:..|.|:...:.|...|..:..|.:
Mouse   131 TLNVLRDDIDNPDQRISQDVERFCRQLSSVTSKLIISPFTLTYYTYQCFQSTGWLGPVSIFGYFI 195

  Fly   243 FAGVFLTRLRRPTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHL 307
            ...:....|..|.....|:::||||:||:.:.::..|:|..|||:..:.|.:.......:|....
Mouse   196 VGTMVNKTLMGPIVTKLVQQEKLEGDFRFKHMQIRVNAEPAAFYRAGLVEHMRTDRRLQRLLQTQ 260

  Fly   308 RKFLEFRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENSGQRLQAYYTYGRML-VKL 371
            |:.:...:.:.|..|.. .|..||:.:..::||.||.    :.|:.|...|....:....: :.|
Mouse   261 RELMSRELWLYIGINTF-DYLGSILSYVVIAIPIFSG----VYGDLSPTELSTLVSKNAFVCIYL 320

  Fly   372 AEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTMVNGNNLAQNAVGSASSNFGPNK 436
            .....:|:.....:|.:||:|.|:.||.:.|.|:::.:.:          ..|:|.:..:.....
Mouse   321 ISCFTQLIDLSTTLSDVAGYTHRIGELQEALLDMSRKSQD----------CEALGESEWDLDKTP 375

  Fly   437 GIMCFE--DNIIRFEKVPLVTPNGD-VLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPT 498
            |....|  |.....::|.::.|:.| .|:::||.::..|.::|:.|..|.||:||.|:||.||..
Mouse   376 GCPTTEPSDTAFLLDRVSILAPSSDKPLIKDLSLKICEGQSLLITGNTGTGKTSLLRVLGGLWEG 440

  Fly   499 WGGKVTKPS----RGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRL-----GHSDEDLMHYLDI 554
            ..|.|...:    .|.|| :||:|:.|.||||:|:|||     ::.:     ...||.::.:|::
Mouse   441 MKGSVQMLADFGPHGVLF-LPQKPFFTDGTLREQVIYP-----LKEIYPDSGSADDERIVRFLEL 499

  Fly   555 VQLTYLEQRENGLDSIED--WIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYS 617
            ..|:.|..|..|||...|  |.||||.||.||::.|||||.:|::|:|||.|||::.:.|.::|.
Mouse   500 AGLSSLVARTGGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEAESELYR 564

  Fly   618 YCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATI 656
            ..:::|:|..:|.||.||...|.:.|:..|.||:|...|
Mouse   565 IGQQLGMTFISVGHRPSLEKFHSWVLRLHGGGSWELTRI 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	165/619 (27%)
		ABC_membrane_2	63..342	CDD:284003	62/293 (21%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	81/216 (38%)
Abcd4	NP_033018.2	YddA	10..606	CDD:226646	167/624 (27%)
		ABC_membrane_2	16..294	CDD:284003	62/293 (21%)
		ABCD_peroxisomal_ALDP	387..598	CDD:213190	81/216 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720