Protein Alignment Pmp70 and pmp-5

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_504689.1
• Gene: pmp-5 / 179056
• WormBaseID: WBGene00004062
• Length: 598
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 171/650 - (26%)
• Similarity: 285/650 - (43%)
• Gaps: 89/650 - (13%)

  Fly    45 KIQYTIAEKKDKKAGKAHVNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQ 109
            |:|  :.|||.:...:     ||:...| |.|::....|     |..::.|..|..||.:..:..
 Worm     3 KLQ--VIEKKFEFGFR-----VFYNLFR-LFPLIYSNTW-----LTLVLTAVTIAASVGNEIVNY 54

  Fly   110 NATVVES----TIIHMNRTK----FKTALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHL 166
            ...|:..    .:|..:..|    |..|.|.|: .|..:..:.|...|.   |.::.|.||...|
 Worm    55 KTGVIPGKFYVALIEKDEPKFWHIFWIASLCYV-GLCLLMALMNFFSWC---LYIQQRKNLVQCL 115

  Fly   167 YSQYLNGYTYYKMSNLDNR-IANADQLLTTDIDKFCESATDLY--SNISKPVLDIFIYVY---RL 225
            :..|.....||:::.:|:. |.|.||.:|.|.||.    |.|.  |.|...:|..||..|   |:
 Worm   116 HKLYYKNNFYYQLNGVDDHGIDNPDQRITQDADKL----TKLLGTSIIPTVLLSPFIISYYGVRV 176

  Fly   226 TVNLGGKTPSILMLYLLFAGVFLTR-LRRPTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGN 289
            ....||....:::.|.|. ||.:.| |..|........:|.||:|||.:..:..|:||.|||:..
 Worm   177 WETAGGWGFGMIVAYFLI-GVIINRILIGPITPWAARVEKAEGDFRYKHVSVRVNAEESAFYKSA 240

  Fly   290 VREKLTLLASYSKLRSHLRKFLEFRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPL------ 348
            ..|.:....|:..|...|..|:.:|..        .::|.|...:|...:.:..:..||
 Worm   241 EFEHVFSDLSFDVLFKRLLNFMCWRFP--------SQFFQSFFDYYGGCMSYILQLFPLFVFHMY 297

  Fly   349 -------LSGENSGQRLQAYYTYGRMLVKLAEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLN 406
                   |||:.|.   .|:|     .:.|.....||......::.|.|:..|::|.:.......
 Worm   298 DNLTPAELSGQISN---NAFY-----FIYLINCFTRLTDLAMNIAELGGYIMRVSEFVDTGKLHQ 354

  Fly   407 KGTYERTMVNGNNLAQNAVGSASSNFGPNKGIMCFEDNIIRFEKVPLVTP-NGDV-LLQELSFEV 469
            .|.........:.|.:.|.|               :||:|..|.:....| |.:: :::.|:|.:
 Worm   355 SGIKNEAFRRNSELPEKASG---------------DDNLIETEHLSFGPPTNSNIRIIENLTFHL 404

  Fly   470 KSGTNVLVCGPNGCGKSSLFRILGELWPTWGGKVTKPSRGKLFYVPQRPYMTLG--TLRDQIIYP 532
            .....:|:.|.:|.||:||.|::.::||..|.......:...:::||:||..:|  :|:.|:::|
 Worm   405 PRNKTLLITGDSGIGKTSLMRVIADMWPHQGILKKHFKKTDAYFLPQKPYFPVGRLSLKQQLVFP 469

  Fly   533 HTRDDMRRLGHSDEDLMHYLDIVQLTYLEQRENGL-DSIE-DWIDVLSGGEKQRIAMARLFYHKP 595
            ...::.:  ..:||:::..|..::|.:|......: ||:: :|.:.||.||:||:..||:...:|
 Worm   470 AEENEEK--SGNDEEIVRILHELKLGHLLPIVGNIHDSVDFEWQETLSPGEQQRLCFARMILAEP 532

  Fly   596 QFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATIDQDK 660
            ..|.|||.|..|...:|..||...|:..||..:|.|||||.:|||:.|:.....|:.|..|...|
 Worm   533 TVAFLDESTCNVDEGMENAMYEMLRKHSITYISVGHRKSLRSHHDFELRIPSSSSFLFHEIHNQK 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	168/641 (26%)
		ABC_membrane_2	63..342	CDD:284003	77/293 (26%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	64/210 (30%)
pmp-5	NP_504689.1	YddA	33..582	CDD:226646	157/595 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820