Protein Alignment Pmp70 and pmp-2

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_495408.1
• Gene: pmp-2 / 174127
• WormBaseID: WBGene00004059
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 384/651 - (58%)
• Similarity: 478/651 - (73%)
• Gaps: 13/651 - (1%)

  Fly    17 GVAGMTAALWIIAYGKMSNKKRKPGYEDKIQYTIAE-KKD-KKAGKAHVNSVFFKQLRQLLPILI 79
            ||.||.|...:|...|...:..|        :.:|: ||| .|..||||:.||..:|.::|.|||
 Worm    22 GVVGMLAVFALIKLYKQDIRGTK--------HLVAKTKKDGSKGQKAHVDGVFLGKLARILKILI 78

  Fly    80 PGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVESTIIHMNRTKFKTALLKYLTALPAISVVT 144
            |||:|.|:..|.|:|.:|:.|:.:|::||..:|.:|::||..|...|.....||:..||||||..
 Worm    79 PGFFSKESFYLILIAVSLLCRTYADVYMIITSTKIEASIIDRNPLLFALEAFKYVLNLPAISVTN 143

  Fly   145 NVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNLDNRIANADQLLTTDIDKFCESATDLYS 209
            .:||:.:.|||||||..|:.|||||||.|:|:|||||||.||.|||||||.|:|:||:...:|||
 Worm   144 AILKFGIAELKLRFRERLSTHLYSQYLKGFTFYKMSNLDTRIQNADQLLTQDVDRFCDGIVELYS 208

  Fly   210 NISKPVLDIFIYVYRLTVNLGGKTPSILMLYLLFAGVFLTRLRRPTGRLTVEEQKLEGEFRYVNS 274
            |:|||:||:|:|::||..:||..:||||..||||.||.||.||||.||||||||.||||:|||||
 Worm   209 NLSKPILDVFLYLFRLGTSLGFSSPSILFSYLLFTGVGLTYLRRPIGRLTVEEQALEGEYRYVNS 273

  Fly   275 RLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLEFRVSMGIIDNIIGKYFASIVGFYAVSI 339
            |||.||||:||||||..||.|::::::.|..||||.:.||.|:|.:|||:.||.|::||:|||..
 Worm   274 RLIMNSEEIAFYQGNQSEKETIMSTFASLVQHLRKIILFRFSIGFVDNIVAKYLATVVGWYAVGS 338

  Fly   340 PFFSENHPLLSGENSGQRLQAYYTYGRMLVKLAEAIGRLVLAGREMSRLAGFTARMTELIKVLSD 404
            .||.:.|....|.:..|.:|.||..|||:.|:|||:|||.||||:|:||:|||:|:..|:.||.|
 Worm   339 SFFDKQHKPFIGMSRNQLMQEYYNSGRMMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVLDD 403

  Fly   405 LNKGTYERTMVNGNNLAQNAVGSASSNFGPNKGIMCFEDNIIRFEKVPLVTPNGDVLLQELSFEV 469
            :|.|.|:|||| |.....:|:  ..|......|.:..:||:|||:.|||||||||||::.|:|||
 Worm   404 VNSGNYKRTMV-GEKEESSAL--IKSELVAGSGNLRVQDNVIRFDNVPLVTPNGDVLIERLNFEV 465

  Fly   470 KSGTNVLVCGPNGCGKSSLFRILGELWPTWGGKVTKPSRGKLFYVPQRPYMTLGTLRDQIIYPHT 534
            .||||||||||||||||||||:||||||.:||.:|||::||||||||||||||||||||||||..
 Worm   466 PSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGTLTKPAKGKLFYVPQRPYMTLGTLRDQIIYPDR 530

  Fly   535 RDDMRRLGHSDEDLMHYLDIVQLTYLEQRENGLDSIEDWIDVLSGGEKQRIAMARLFYHKPQFAI 599
            ..||.|.|.||.||...|:.||||::.:||.|..:::||:|||||||||||||||||||||||||
 Worm   531 PLDMIRKGVSDSDLEQMLENVQLTHILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAI 595

  Fly   600 LDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATIDQDKDHFG 664
            ||||||||||||||.||..|||..|||||||||||||.:|:|.|..||||||.|..||...|.||
 Worm   596 LDECTSAVSVDVEGAMYRLCREKNITLFTVSHRKSLWKYHEYSLYMDGRGSYRFEQIDDQSDQFG 660

  Fly   665 S 665
            |
 Worm   661 S 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	377/637 (59%)
		ABC_membrane_2	63..342	CDD:284003	158/278 (57%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	155/204 (76%)
pmp-2	NP_495408.1	3a01203	1..649	CDD:273360	377/637 (59%)
		ABC_membrane_2	62..341	CDD:284003	158/278 (57%)
		ABCD_peroxisomal_ALDP	442..647	CDD:213190	155/204 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165988
Domainoid	1	1.000	320	1.000	Domainoid score	I664
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2140
Inparanoid	1	1.050	753	1.000	Inparanoid score	I286
Isobase	1	0.950	-	0	Normalized mean entropy	S1054
OMA	1	1.010	-	-		QHG53776
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	1	1.000	-	-		otm14445
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	1	1.100	-	-	LDO	PTHR11384
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3716
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750