Protein Alignment Pmp70 and pmp-1

DIOPT Version :9

• Sequence 1: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_495407.1
• Gene: pmp-1 / 174126
• WormBaseID: WBGene00004058
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 678
• Identity: 367/678 - (54%)
• Similarity: 474/678 - (69%)
• Gaps: 33/678 - (4%)

  Fly     5 LSKL---------ANNQSAIVGVAGMTAALWIIAYGKM-SNKKRKPGYEDKIQYTIAEKKDKKA- 58
            ||||         .|...|.||:.|      .|...|: |...|..|....:..|:.....||.
 Worm     4 LSKLQLLNSTLTYKNWSPAFVGIFG------CITIAKIYSASFRNEGKGLSLSETVGSGDVKKGK 62

  Fly    59 GKAHVNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVESTIIHMNR 123
            .||.:|:.||.:|::||.|||||.:|.|...:.::...|:.|:::|::||.|||.||::|:..:.
 Worm    63 TKASLNAEFFAKLKKLLKILIPGPFSSEVFYMIVIGFVLLARTIADVYMITNATSVEASIVDRSP 127

  Fly   124 TKFKTALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYYKMSNLDNRIAN 188
            ..|..::.||...|||||::..:||:||.|||||||.|||.:||.:||.|:|||::||||:||.|
 Worm   128 IMFAMSVFKYFLNLPAISLINALLKFSLSELKLRFRENLTKYLYGKYLGGFTYYQISNLDSRIQN 192

  Fly   189 ADQLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTPSILMLYLLFAGVFLTRLRR 253
            .|||||.|::|||:...:||||::||:||:|:||::|...||.:.|.:|..||:.:.|.||:|||
 Worm   193 PDQLLTQDVEKFCDGIVELYSNMTKPILDVFLYVFKLGRALGWEGPGLLFGYLMASMVVLTKLRR 257

  Fly   254 PTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLEFRVSMG 318
            |..:||||||.||||:||||||||.||||:||||||..||..|:.|::.|..||||.:.||.::|
 Worm   258 PIAKLTVEEQVLEGEYRYVNSRLIMNSEEIAFYQGNKPEKQALMGSFNNLVYHLRKTIMFRFTLG 322

  Fly   319 IIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENSGQRLQAYYTYGRMLVKLAEAIGRLVLAGR 383
            .:|||:|||..:|||:.|.:..||..|:...:..:..:.:|..|..|||::||:||:|||.||||
 Worm   323 FVDNIVGKYITNIVGWVACAKTFFDVNNEKFNEMDRNELMQELYNNGRMMLKLSEALGRLALAGR 387

  Fly   384 EMSRLAGFTARMTELIKVLSDLNKGTYERTMV------NGNNLAQNAVGSASSNFGPNKGIMCFE 442
            :|:||:|||.|:..|:|||.|:..|.:|:..|      .|..|...| ||         |.:..:
 Worm   388 DMTRLSGFTTRVDTLMKVLDDMKAGRFEKAQVADESGEEGQRLMLKA-GS---------GKLLAQ 442

  Fly   443 DNIIRFEKVPLVTPNGDVLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPTWGGKVTKPS 507
            ||:|:|::|||||||||:|::.|||||.||.|||||||||||||||||.||||||..||.:|||:
 Worm   443 DNMIKFDEVPLVTPNGDILIESLSFEVPSGRNVLVCGPNGCGKSSLFRTLGELWPVMGGTLTKPA 507

  Fly   508 RGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRLGHSDEDLMHYLDIVQLTYLEQRENGLDSIED 572
            :||||||||||||||||||||:|||.|..||:..|.||:||...|:.||||.:.:||.|..:::|
 Worm   508 KGKLFYVPQRPYMTLGTLRDQVIYPDTSFDMKMKGMSDKDLEQMLENVQLTNILEREGGWSAVQD 572

  Fly   573 WIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWA 637
            |:|||||||||||||||||||||||||||||||||||||||.||..|||:.|||||||||||||.
 Worm   573 WMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGAMYRLCREMNITLFTVSHRKSLWK 637

  Fly   638 HHDYYLQFDGRGSYEFATIDQDKDHFGS 665
            :|:|.|..||||||.|..||...|.|||
 Worm   638 YHEYSLYMDGRGSYRFEQIDDQSDQFGS 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	360/664 (54%)
		ABC_membrane_2	63..342	CDD:284003	145/278 (52%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	152/204 (75%)
pmp-1	NP_495407.1	3a01203	1..653	CDD:273360	360/664 (54%)
		ABC_membrane_2	67..346	CDD:284003	145/278 (52%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	152/204 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165989
Domainoid	1	1.000	320	1.000	Domainoid score	I664
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2140
Inparanoid	1	1.050	753	1.000	Inparanoid score	I286
Isobase	1	0.950	-	0	Normalized mean entropy	S1054
OMA	1	1.010	-	-		QHG53776
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	1	1.000	-	-		otm14445
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	1	1.100	-	-	O	PTHR11384
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.720