DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment parvin and actn3a

DIOPT Version :9

Sequence 1:	NP_001285464.1	Gene:	parvin / 32990	FlyBaseID:	FBgn0052528	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_571597.1	Gene:	actn3a / 58037	ZFINID:	ZDB-GENE-000329-9	Length:	896	Species:	Danio rerio

Alignment Length:	143	Identity:	40/143 - (27%)
Similarity:	68/143 - (47%)	Gaps:	26/143 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 TSEY----DDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVY 290
            |.||    ||    .::|.|   :|.|.:|..  :|:...:.|.||.|...:|.::..|||:|:.
Zfish    18 TEEYMIQEDD----WDRDLF---LDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRNGLK 73

  Fly   291 LCLLMGLLGGFFVPLHE-----FHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLK 350
            |.||:..:.|..:|..:     ||        .::||..|.|.:...|:.......|:||:.:||
Zfish    74 LMLLLEAISGERLPKPDKGKMRFH--------KIANVNKALDFISSKGVKLVSIGAEEIVDGNLK 130

  Fly   351 STLRVLYSLFTMF 363
            .||.:::::...|
Zfish   131 MTLGMIWTIILRF 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
parvin	NP_001285464.1	CH	92..192	CDD:278723
parvin	NP_001285464.1	CH	258..359	CDD:278723	29/105 (28%)
actn3a	NP_571597.1	CH	41..139	CDD:278723	29/107 (27%)
		CH	154..259	CDD:237981
		Spectrin	283..392	CDD:278843
		SPEC	404..631	CDD:238103
		Spectrin	639..742	CDD:278843
		FRQ1	752..896	CDD:227455
		EFh	759..821	CDD:238008
		EFhand_Ca_insen	826..892	CDD:285885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910