DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment parvin and parvaa

DIOPT Version :9

Sequence 1:	NP_001285464.1	Gene:	parvin / 32990	FlyBaseID:	FBgn0052528	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001002872.1	Gene:	parvaa / 442922	ZFINID:	ZDB-GENE-040721-2	Length:	372	Species:	Danio rerio

Alignment Length:	360	Identity:	203/360 - (56%)
Similarity:	272/360 - (75%)	Gaps:	2/360 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PKSPHTPTAIKKGEKEDSFWDKF-STLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYAL 70
            |||| ||.:....:|:|||..|. .||.|::..:||.::||||..||:.|.||:.:::.|||..|
Zfish    12 PKSP-TPKSPSSRKKDDSFLGKLGGTLVRRKKAKEVSELQEEGMNAINLPLSPTPFELHPEDIML 75

  Fly    71 REHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKK 135
            .|:|.|.::||.|.||.::.:|.::|:|||||.|..:||||:.|.||:||||||.||:|||.|:|
Zfish    76 EENEVRTMVDPNSKSDRKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLEGEK 140

  Fly   136 LDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPV 200
            |:|.||||||..|.:||..||:.:|..|....:..||:|.|||:|:|||||||||||.:|||||:
Zfish   141 LNVAEVTQSEIAQKQKLQTVLERINDALKVSTRSIKWNVDSVHAKSIVAILHLLVALSQHFRAPI 205

  Fly   201 RLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLIT 265
            |||::|.:.||:.:|..|:|.:::..|:||...:.|..|.|:||||||.|.|||||:||||:|||
Zfish   206 RLPDHVSIQVVVVQKREGILQSRQVMEEITGNTEALSGRHERDAFDTLFDHAPDKLSVVKKTLIT 270

  Fly   266 FVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQ 330
            ||||||.|||.|:::|:|.|.|||||.||||||.|:||||:.|.|||::.||.|.||:|:|:|||
Zfish   271 FVNKHLNKLNLEVAELDTQFADGVYLVLLMGLLEGYFVPLYNFFLTPENFDQKVHNVSFSFELMQ 335

  Fly   331 DVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRD 365
            |.|:.:||.|||||||.:|||||||:|:|||.:|:
Zfish   336 DGGMERPKPRPEDIVNCNLKSTLRVIYNLFTRYRN 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
parvin	NP_001285464.1	CH	92..192	CDD:278723	59/99 (60%)
parvin	NP_001285464.1	CH	258..359	CDD:278723	69/100 (69%)
parvaa	NP_001002872.1	CH	96..197	CDD:278723	59/100 (59%)
parvaa	NP_001002872.1	CH	263..364	CDD:278723	69/100 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578638
Domainoid	1	1.000	154	1.000	Domainoid score	I4212
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	403	1.000	Inparanoid score	I1875
OMA	1	1.010	-	-		QHG52959
OrthoDB	1	1.010	-	-		D373611at33208
OrthoFinder	1	1.000	-	-		FOG0002943
OrthoInspector	1	1.000	-	-		otm24706
orthoMCL	1	0.900	-	-		OOG6_105758
Panther	1	1.100	-	-	O	PTHR12114
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2710
SonicParanoid	1	1.000	-	-		X1944
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900