| Sequence 1: | NP_001035757.1 | Gene: | HSF4 / 3299 | HGNCID: | 5227 | Length: | 492 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001036555.1 | Gene: | Hsf / 37068 | FlyBaseID: | FBgn0001222 | Length: | 733 | Species: | Drosophila melanogaster |
| Alignment Length: | 564 | Identity: | 169/564 - (29%) |
|---|---|---|---|
| Similarity: | 254/564 - (45%) | Gaps: | 135/564 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 15 SPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYG 79
Human 80 FRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALR-GDD-GRWRPEDLGRLLGE 142
Human 143 VQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLFGPLQAGPSNAGGKR 207
Human 208 KLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRAR-----------GPI 261
Human 262 ISDIPED------SPSPEG---------TRLSPSSDGRREKGLALLKE---------EPASPGGD 302
Human 303 GEAG---------------LALAPNECD-FCVTAPPPLPVAVV---------QAILEGKGSFSPE 342
Human 343 GPRNAQQPEPGDPREIPDRGPLGLESGD-----RSPE--------SLLPPMLLQPPQESVEP--- 391
Human 392 AGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVK------GLNSPSPGK------D 444
Human 445 PTLGAPLLLDVQAALGGPALGLPGALTIYSTPES-RTASYLGPE 487 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HSF4 | NP_001035757.1 | HSF | 16..120 | CDD:214654 | 57/103 (55%) |
| Rootletin | <110..175 | CDD:373494 | 23/66 (35%) | ||
| Hydrophobic repeat HR-A/B | 129..203 | 27/73 (37%) | |||
| Interactions with DUSP26, MAPK1 and MAPK2 | 245..322 | 25/127 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 246..285 | 15/64 (23%) | |||
| Vert_HS_TF | 259..>443 | CDD:368967 | 51/254 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 337..400 | 18/78 (23%) | |||
| Hydrophobic repeat HR-C | 364..389 | 9/37 (24%) | |||
| Hsf | NP_001036555.1 | HSF | 45..148 | CDD:214654 | 57/103 (55%) |
| Vert_HS_TF | <607..711 | CDD:284062 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165155319 | |
| Domainoid | 1 | 1.000 | 126 | 1.000 | Domainoid score | I5413 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1154048at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000255 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41758 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR10015 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2153 |
| SonicParanoid | 1 | 1.000 | - | - | X160 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.980 | |||||