DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14234 and Tmem198

DIOPT Version :9

Sequence 1:	NP_001356951.1	Gene:	CG14234 / 32988	FlyBaseID:	FBgn0031065	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_036021589.1	Gene:	Tmem198 / 319998	MGIID:	2443133	Length:	440	Species:	Mus musculus

Alignment Length:	374	Identity:	92/374 - (24%)
Similarity:	156/374 - (41%)	Gaps:	97/374 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 CTPT-------------APEP-------------------LAAILWAIFAVFGIVYALLGYRCLR 69
            |||:             .|||                   |.|::..:..:||:||...||||.:
Mouse    77 CTPSFARKLRSPPAQLLPPEPDDTFWGAPCEQPLERRYQALPALVCIMCCLFGVVYCFFGYRCFK 141

  Fly    70 AVGFLSGLLVGANGIFIL---QDFQITFLGKPADSALAIVAGLL-GAVLGSTYPVASVLISAFAG 130
            ||.||:|||.|:..||:|   :....|.|...|.:.:|:..||| |.|......|...|:....|
Mouse   142 AVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLG 206

  Fly   131 ALLSGAAMAVCVATF-PDNEFGYREIYVAVVGGAVICSVLTLCCVKYVTILTSSIVGTAMILSAI 194
            .||:.||:......: |.:.:|...:   ::||.::|::|||...:.:|.|.:::.|.|:|.:|.
Mouse   207 LLLAAAALLGSAPYYQPGSVWGPLGL---LLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAA 268

  Fly   195 DFFTHGLETINWII-GMRPHPSPPPCY-GGLLIAAWPVTIVLSIMVQCFITAWRVDHRKRVYMRH 257
            |:|...|....::: .:|..|.||.|: ...|:|.||:..::.::||..:|..|..|.:.|..|.
Mouse   269 DYFAELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQ 333

  Fly   258 HNHPGHAHGAHLPHSQQQAGPNHGIAPVRRSQSRTRETREEARQRK------------------- 303
            ...                        |:..:.|.:|.|:|.|::|
Mouse   334 RRR------------------------VQLMRIRQQEERKEKRRKKRPPRAPPRGPRAPPRPGPP 374

  Fly   304 ----FRYLYQVRTARGDIISQNFVSALQKR--------IQLSGTETPSE 340
                .|....::...||::|.:::.:.:.|        ...|.|:|..|
Mouse   375 DPAYRRRPVPIKRFNGDVLSPSYIQSFRDRQTGSSLSSFMASPTDTDYE 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14234	NP_001356951.1	DUF4203	55..240	CDD:338988	62/191 (32%)
CG14234	NP_001356951.1	SelP_N	<249..288	CDD:335846	4/38 (11%)
Tmem198	XP_036021589.1	DUF4203	120..316	CDD:404726	62/198 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836821
Domainoid	1	1.000	92	1.000	Domainoid score	I7600
eggNOG	1	0.900	-	-		E1_28JN9
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I4964
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45665
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003355
OrthoInspector	1	1.000	-	-		otm43559
orthoMCL	1	0.900	-	-		OOG6_105348
Panther	1	1.100	-	-	LDO	PTHR31247
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6324
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.790