Protein Alignment CG12531 and SLC7A14

DIOPT Version :10

• Sequence 1: NP_608350.2
• Gene: CG12531 / 32986
• FlyBaseID: FBgn0031064
• Length: 812
• Species: Drosophila melanogaster
• Sequence 2: NP_066000.2
• Gene: SLC7A14 / 57709
• HGNCID: 29326
• Length: 771
• Species: Homo sapiens
• Alignment Length: 780
• Identity: 339/780 - (43%)
• Similarity: 460/780 - (58%)
• Gaps: 104/780 - (13%)

  Fly    31 KLIRTKDVKQLQD--GNAQPQKPKLTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVII 93
            :::|||.|:.:.:  |.......||.:.|.|:||.|||:|||.|||||:|:|:||:::||||||:
Human    25 RILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIV 89

  Fly    94 SFIIAAIASIFSGACYAEFGVRVPHTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACAL 158
            ||||||:|||.||.||||||||||.|:||||.||||.|||||||.||||:||||||||:|.|.||
Human    90 SFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASAL 154

  Fly   159 SSSFDSLTGNAIARTISESIGTIFG------KPPDFIAFGITLLMTCVLAMGASKSVIFNHSLNA 217
            ||.||||..:.|:|.:::|:||:.|      ..||.:|..|.:::|.::|:|...|:.||:.||.
Human   155 SSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNV 219

  Fly   218 VNLATWVFVMAAGLFYVDTKTWSEHQGFLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQK 282
            :|||.|||:|.||||:::.|.|:|.| |||:|||||..||||||||||||||||||||||.||..
Human   220 LNLAVWVFIMIAGLFFINGKYWAEGQ-FLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNT 283

  Fly   283 SIPKAIVGSLVVVLIAYVSVSLVLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSV 347
            |||.||..|||:.|.||||||::|||:|||..|:|.:.|::|:........:.|||||:.|||:|
Human   284 SIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTV 348

  Fly   348 AMFGSMFPMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSI 412
            ::.||:|||||||||||.|||:||.|:.:...|..|.:|.|.||..|||:||.|.|..|:|||||
Human   349 SLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSI 413

  Fly   413 GTLLAYTLVSTCVLVLRYQPHS--TSLVELLPAQLRTPVAHGTASDSRSHVTPAEVLEVPGKLTI 475
            ||||||||||.|||:|||||.|  ...|:.| ::..|....|..:|..
Human   414 GTLLAYTLVSVCVLLLRYQPESDIDGFVKFL-SEEHTKKKEGILADCE----------------- 460

  Fly   476 KRVTRGMSDSDDSFIDDSPEGFLGGR------DDQFLVSDRSENKFYGSVHGAPT-GPTGQATAF 533
            |.....:|:.|:  .........|.:      |::.|:. :|:...|...|  |. |.....|..
Human   461 KEACSPVSEGDE--FSGPATNTCGAKNLPSLGDNEMLIG-KSDKSTYNVNH--PNYGTVDMTTGI 520

  Fly   534 DA--------------MGLNFVTRKIHDYAYLCPGFFPWINPGQATAESGMYVTKLVGIMFGLIF 584
            :|              :|.::.|.:|.   ...||     ...:.||.:|..||..|.::|.|:|
Human   521 EADESENIYLIKLKKLIGPHYYTMRIR---LGLPG-----KMDRPTAATGHTVTICVLLLFILMF 577

  Fly   585 FLDLFAAIG---------WSGGLAAFIYFILFIGIFVILLIISRQPQNRYALAFLTPGLPFIPAI 640
            ....|...|         |:..|...:..::...:||||    :||:|...|.::.|.|||:||.
Human   578 IFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVIL----QQPENPKKLPYMAPCLPFVPAF 638

  Fly   641 AITVNIYLIFKLSILTLVRFTVWMSLGFIMYFYYGITHSSLEQASDDLELH--------VDYSKN 697
            |:.|||||:.|||.:|.:||.||..:|.::||.|||.:|:||.::.:..||        ||...:
Human   639 AMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFS 703

  Fly   698 VEEKAVWDQQSYNQTHEPVWASKEVKQPSTEQRYNY---------GKTTSSSSSAQGSSRSGQGS 753
            |||...:..:..:|..   |..     |:.::.:.|         |:|   ||.|:..|:..|.|
Human   704 VEEGFSYATEGESQED---WGG-----PTEDKGFYYQQMSDAKANGRT---SSKAKSKSKHKQNS 757

  Fly   754  753
            Human   758  757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12531	NP_608350.2	2A0303	52..679	CDD:273330	312/664 (47%)
SLC7A14	NP_066000.2	2A0303	48..677	CDD:273330	312/664 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	736..771		8/25 (32%)