DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14230 and ROS3

DIOPT Version :9

Sequence 1:	NP_608349.1	Gene:	CG14230 / 32984	FlyBaseID:	FBgn0031062	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_200621.1	Gene:	ROS3 / 835925	AraportID:	AT5G58130	Length:	748	Species:	Arabidopsis thaliana

Alignment Length:	792	Identity:	152/792 - (19%)
Similarity:	245/792 - (30%)	Gaps:	271/792 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GSTRFFLADLPTRTSESDLQILFQDYGHVEHVDLKRKEQDGATKVIAFVTVQTDDAQYCVNELK- 65
            |..|..:..|.......||..:|...|.|:.|:..|      ||..:|..:  |.:....|.|.
plant     8 GGVRLHVGGLGESVGRDDLLKIFSPMGTVDAVEFVR------TKGRSFAYI--DFSPSSTNSLTK 64

  Fly    66 ---------WQKLHGEKLRVSLAKESFLDRLKREREENQRREQGEPDESEVRAPSS--------- 112
                     |:   |.:||:..|||.:|.|||||.|     ......::.::|||.
plant    65 LFSTYNGCVWK---GGRLRLEKAKEHYLARLKREWE-----AASSTSDNTIKAPSDSPPATHLNI 121

  Fly   113 --------QLLVQSGQNKR--------------RVFGEDEEIGDDEVAP-ELLITKKRAANSMHN 154
                    :.:..||..|.              |.|.:.||..:..:.| |:.:....|.|
plant   122 FFPRLRKVKPMPLSGTGKHKYSFQRVPVSSSLPRSFCDCEEHSNSSLTPREIHLHDLEAVN---- 182

  Fly   155 GRIVIQQEHDVKPLHVI-------------EQHRKAAKQ------------KPDANVSQAEQKRK 194
               |.:||.:|..::.:             |.:...|.|            ..|:.:....:|||
plant   183 ---VGRQEAEVNVMNSVMNKLFEKNNVDPEEDNEIEADQDNLIINVASSGNDMDSALDMLSRKRK 244

  Fly   195 ESLNKM----------RQGHQQKKSAIQQALSVISV---EGSQAKRIKFSDAE--------EEEA 238
            ..|||.          |:|:....|..:|.:|:...   |.|||.|.|...:|        |...
plant   245 SILNKKTPSEEGYSEGRKGNLTHPSKNRQTISLEETGRQESSQAIRGKKKPSEVVPDKSSDEPSR 309

  Fly   239 SKPVQKA--------KIQKRDLFENDDDEE-----------EEQIVLPQHKGKKGERLVEMQSKQ 284
            :|.::::        |...:.|..|.:..:           ..:.|.|..:......|...::.:
plant   310 TKDLEQSIDNISWSQKSSWKSLMANGNSNDFSVSSFLPGVGSSKAVQPAPRNTDLAGLPSRENLK 374

  Fly   285 SIDPRFRITSNFVNE----------EEEAELEDQPEPEESERKWHMNILEQV----VGHAITSAN 335
            ....|.|:||..:.|          ::...:.|..|.::|:...:....|.:    ...::...:
plant   375 KKTKRKRVTSTIMAEDLPVSDDIKRDDSDTMADDIERDDSDAVEYYTACESMADDTASDSVAERD 439

  Fly   336 DKDGKSPKNK-KMLRFDPAKEGHQKLMRQKQPKEEEEKKEETSSTKAKTADAGNSQASAVSKTAF 399
            |.|....... ..:..|||.:        ...:.::....|..:.....||...|.:.|.|....
plant   440 DSDAVEDDTAIDSMADDPASD--------SVAESDDGDAVENDTAIDSMADDTVSNSMAESDDGD 496

  Fly   400 YIVTDTLRDSL--NTRGEGFSLLDMFGSAPEKEVAKRQDQLEKLGHEKILVGKTSANKLGLATLN 462
            .:..||..||:  :|..      |..||.....:|.             .|..||...:.|..:.
plant   497 NVEDDTAIDSMCDDTAN------DDVGSDDSGSLAD-------------TVSDTSVEAVPLEFVA 542

  Fly   463 PFSYDSSDSEDETEVKPK--QEQEQEQELEVSKENKAQ-------PAKKSG---------QKRNK 509
            ....||.|.:...|....  ::...|:|..|.|||...       |.|.|.         ||.:.
plant   543 NTEGDSVDGKSNVEKHENVAEDLNAEKESLVVKENVVDEEEAGKGPLKASNKSTGGSSWLQKASW 607

  Fly   510 NKL------ESFFIPRNDPRLKE------------GAKFFKS--TKAVVDHAEY----------- 543
            .:|      .||.|.:..|.|..            |.:|..|  |.:.:...:|
plant   608 TQLVSDKNTSSFSITQLFPDLTSDKGEAAGVINNVGNQFSNSNQTASAMKQTDYASSSGGFVAAG 672

  Fly   544 -----------DQVKNRL--------------KLLITKKI------------------AKAKKSL 565
                       |:.:.||              |.:|.:|:                  |||||:|
plant   673 VPVDSTPVRSLDENRQRLNGKNVSEGAKLGAKKKIIKRKVGSGDTCTFMRSSTSLKEWAKAKKAL 737

  Fly   566 PSKDIKLQRNKK 577
            ..     .|.||
plant   738 SE-----PRRKK 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14230	NP_608349.1	RRM	<3..>115	CDD:223796	32/138 (23%)
CG14230	NP_608349.1	RRM_SF	7..77	CDD:240668	18/79 (23%)
ROS3	NP_200621.1	PLN03213	1..748	CDD:178752	152/792 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005063
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000