Protein Alignment CG14230 and Nol8

DIOPT Version :9

• Sequence 1: NP_608349.1
• Gene: CG14230 / 32984
• FlyBaseID: FBgn0031062
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001258326.1
• Gene: Nol8 / 70930
• MGIID: 1918180
• Length: 1165
• Species: Mus musculus
• Alignment Length: 628
• Identity: 139/628 - (22%)
• Similarity: 255/628 - (40%)
• Gaps: 150/628 - (23%)

  Fly    28 GH---VEHVDLKRKEQDGATKVIAFVTVQTDDAQYCVNELKWQKLHGEKLRVSLAKESFLDRLKR 89
            ||   ::|.|..|...:..:|              |||                ...|.|...:.
Mouse   595 GHHSSLKHEDHNRSLMENGSK--------------CVN----------------GSSSKLTSCQP 629

  Fly    90 EREENQRREQGEPDESEVRAPSSQLLVQSGQNKRRVFGEDEEIGDDEVAPELLITKKRAANSMH- 153
            .::.|        |.:.::.|..|...:: ||.:.:.....:.|.....|..|..|  |..|:|
Mouse   630 AKKVN--------DPNHIQPPKRQCTFEN-QNHKVMSSTSCDKGSTNPLPGPLPLK--AKTSLHL 683

  Fly   154 -----------------NGRIVIQQEHDVKPLHVIEQHRKAAKQKP--------------DANVS 187
                             ..|..:::|.  ..|..:|...|::|..|              |:|.|
Mouse   684 SANSHKVDSDGDACHWPESRKALEKER--TNLSNLESLEKSSKVSPREDPQKSPAGFSLSDSNAS 746

  Fly   188 -------QAE--QKRKESLNKMRQGHQQKKSAIQQALSVISVEGSQAK-RIKF---SDAEEEEAS 239
                   |||  |||..:|...::..:.:|..:..||:.:.......| .|.|   :::|.||.|
Mouse   747 CINAKDKQAEDNQKRLAALAAWQKAREVQKKLVHSALANLDGHPEDKKTHIVFASDNESETEETS 811

  Fly   240 --------KPVQKAKIQKR--DLFENDDDEEEEQ-------IVLPQHKGKKGERLVEMQSKQSID 287
                    |.:.|..:.|.  .||::.|||:.:.       .:.||.:|:.|::|:::||:...|
Mouse   812 TQEQSCPEKELMKESVSKSPGKLFDSSDDEDSDSKEDSTRFSIKPQFEGRAGQKLMDLQSQFGSD 876

  Fly   288 PRFRITSNFV---NEEEEAEL-EDQPEPEE--SERKWHMNILEQVVGHAITSANDKDGKSPKN-K 345
            .|||:.|.|:   :|:|:.|| ||:...:|  :|:|..:|:::.|:...:.:..:|...:.|. |
Mouse   877 ERFRMDSRFLESDSEDEKKELNEDKVNEDELAAEKKKTLNVVQSVLNINVNNPTNKGSVAAKKFK 941

  Fly   346 KMLRFDPAKEGHQKLMRQKQPKEEEEKKEETSSTKAKTADAGNSQASAVSKTAFYIVTDTLRDSL 410
            .::.:||.|..|....|    |:|:::||..::.|.|..:|  .:...||:..:|.:...|::..
Mouse   942 DIVHYDPTKHDHAIYER----KQEDKEKESKATRKKKKEEA--EKLPEVSQDMYYNIAADLKEIF 1000

  Fly   411 NTRGEGFSLLDMFGSAPEKEVAKRQDQLEKLGHEKILVGKTSANKLGLATLNPFSYDSSDSEDET 475
            .:         |..:..::|...|.:...:.|..||...:|.|.:....|...||:..|.::||.
Mouse  1001 QS---------MSNTDEKEEDVPRTEAGAREGTGKIRNAETLACEPEQTTGFTFSFFDSATKDEK 1056

  Fly   476 E-------VK---------PKQEQEQEQELEVSKENKAQPAKKS-GQKRNKNK-LESFFIPRNDP 522
            :       ||         |:.:....:|.::::|  |..:|.| |:...:|: :..||...||.
Mouse  1057 DATYRIELVKHGKIVCPNDPRFQDSSSEEEDIAEE--ADHSKPSPGEAVPENEAIRFFFFSENDD 1119

  Fly   523 RLKEGAKFFKSTKAVVDHAEYDQVKNRLKLLITKKIAKAKKSL 565
            ||:....|:......:....::...:.|.|...||..:||:.:
Mouse  1120 RLRGSNLFWSGMGGSISRNSWEARTSSLLLECRKKHKEAKRKV 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14230	NP_608349.1	RRM	<3..>115	CDD:223796	15/89 (17%)
		RRM_SF	7..77	CDD:240668	9/51 (18%)
Nol8	NP_001258326.1	RRM_NOL8	27..106	CDD:240672

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843057
Domainoid	1	1.000	124	1.000	Domainoid score	I5547
eggNOG	1	0.900	-	-		E1_KOG4365
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4288
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005063
OrthoInspector	1	1.000	-	-		oto92464
orthoMCL	1	0.900	-	-		OOG6_105160
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1972
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.770