DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14230 and Nol8

DIOPT Version :9

Sequence 1:	NP_608349.1	Gene:	CG14230 / 32984	FlyBaseID:	FBgn0031062	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	XP_006253748.1	Gene:	Nol8 / 361221	RGDID:	1309551	Length:	1159	Species:	Rattus norvegicus

Alignment Length:	439	Identity:	101/439 - (23%)
Similarity:	193/439 - (43%)	Gaps:	70/439 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 AKQKPDANVSQAEQKRKESLNKMRQGHQQKKSAIQQALSVISVEGSQAKR---IKF-SDAEEE-- 236
            ||.|.    ::..|||..:|...:...:.:|..:..||:  :::|....|   |.| ||.|.|
  Rat   743 AKDKH----AEDNQKRLAALAAWQNAREVQKKLVHSALA--NLDGRPENRKTHIVFASDNESETE 801

  Fly   237 -----EASKP----VQKAKIQKRD--LFENDDDEEEEQ-------IVLPQHKGKKGERLVEMQSK 283
                 |.|.|    |::..::|..  ||::.||||.:.       .:.||.:|:.|::|:::||.
  Rat   802 ETSTHEQSCPEKELVKQESVRKASGKLFDSSDDEESDSKEDSTRFSIKPQFEGRAGQKLMDLQSH 866

  Fly   284 QSIDPRFRITSNFV---NEEEEAELEDQPEPEE---SERKWHMNILEQVVGHAITSANDKDGKSP 342
            ...|.|||:.|.|:   :|:|:.||.:....|:   :|:|..:::::.|:..::.:...|...:.
  Rat   867 FGSDERFRMDSRFLESDSEDEQKELNENTVDEDELAAEKKKTLSVVQSVLNISVNNPTSKGSVAA 931

  Fly   343 KN-KKMLRFDPAKEGHQKLMRQKQPKEEEEKKEETSSTKAKTADAGNSQASAVSKTAFYIVTDTL 406
            |. |.::.:||.|..|....|    |:|:::||..:..|.|..:|  .:...||:..:|.:...|
  Rat   932 KKFKDIVHYDPTKHDHAIYER----KQEDKEKESKAKRKKKKEEA--EKLPEVSQDMYYNIATDL 990

  Fly   407 RDSLNTRGEGFSLLDMFGSAPEKEVAKRQDQLEKLGHEKILVGKT----SANKLGLATLNPFSYD 467
            ::...:         |..:..::|...|.:...:.|..:|...:|    |....|. |.:.|...
  Rat   991 KEIFQS---------MKNTDEKEEDTSRNEAYAREGAGEIRNAETLTCGSEQTAGF-TFSFFDSA 1045

  Fly   468 SSDSEDET-------------EVKPKQEQEQEQELEVSKENKAQPAKKSGQKRNKNKLESFFIPR 519
            :.|.:|:|             :..|:.:....:|.:|::|...:..........|..:..||...
  Rat  1046 TKDVKDDTYRVEPVRRGKTVCQNDPRFQDSSSEEEDVTEEADHRKTSLGEAVPEKETIRFFFFSE 1110

  Fly   520 NDPRLKEGAKFFKSTKAVVDHAEYDQVKNRLKLLITKKIAKAKKSLPSK 568
            ||.||:....|:......:..:.::...:.|.|...||..:||:.:.:|
  Rat  1111 NDDRLRGSDLFWSGAGGGISRSSWEARTSSLLLDCRKKHKEAKRKVKTK 1159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG14230	NP_608349.1	RRM	<3..>115	CDD:223796
CG14230	NP_608349.1	RRM_SF	7..77	CDD:240668
Nol8	XP_006253748.1	RRM	<26..>151	CDD:223796
Nol8	XP_006253748.1	RRM_NOL8	33..112	CDD:240672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346561
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4203
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005063
OrthoInspector	1	1.000	-	-		oto96029
orthoMCL	1	0.900	-	-		OOG6_105160
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.880