DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14230 and SPBP16F5.06

DIOPT Version :9

Sequence 1:	NP_608349.1	Gene:	CG14230 / 32984	FlyBaseID:	FBgn0031062	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_595780.1	Gene:	SPBP16F5.06 / 2541269	PomBaseID:	SPBP16F5.06	Length:	478	Species:	Schizosaccharomyces pombe

Alignment Length:	556	Identity:	114/556 - (20%)
Similarity:	208/556 - (37%)	Gaps:	136/556 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RFFLADLPTRTSESDLQILFQDYGHVEHVDLKRKEQD-GATKVIAFVTVQTDDAQYCVNELKWQK 68
            |.::..|.:....|||:..|..:|.|.::::..|... |..:..|::..:||       |.||||
pombe     6 RIYVGGLSSSIESSDLESRFSRFGSVSNLEIINKSTPVGTIQRFAYLNFRTD-------EDKWQK 63

  Fly    69 ---------LHGEKLRVSLAKESFLDRLKREREENQRREQGEPDESEVRAPSSQLLVQSGQNKRR 124
                     ..|.|||:..|:..:|.:|::|::...                    :||..|
pombe    64 CKSYLSNATFKGSKLRIEEARPYYLVKLQQEKKIAD--------------------LQSTNN--- 105

  Fly   125 VFGEDEEIGDDEVAPELLITKKRAANSMHNGRIVIQQEHDVKPLHVIEQHRKAAKQKPDANVSQA 189
                ||:..|..       :|....:.:.:|.|::..:|. |.:.|:          .|::|
pombe   106 ----DEKNEDHS-------SKVDLEDPVFHGEIIVPGKHS-KNMQVV----------TDSDV--- 145

  Fly   190 EQKRKESLNKMRQGHQQKKSAIQQALSVISVEGSQAKRIKFSDAEEEEASKPVQKAKIQK----- 249
               ||:   ..|:|  .||....:|:.|:.:.....|:.:|        ..|:.|..:||
pombe   146 ---RKD---PPRKG--WKKGPYGRAIVVLRMYNKNTKKTRF--------FYPLGKNCLQKLWGRV 194

  Fly   250 -------RDLFENDDDEEEEQIVLPQHKGKKGER-LVEMQSK-------QSIDPRFRITSNFVNE 299
                   ...:::|.||      ...:.||:..| .:.||:|       |..|..|.:.:|...|
pombe   195 ETNMDNTTAFYDSDHDE------YVSYGGKRASRDKIRMQAKLGIKASTQKDDNDFELLNNTTGE 253

  Fly   300 -EEEAELEDQPEPEESERKWHMNILEQVVGHAITSANDKD-GKSPKNKKMLRFDPAKEGHQKLMR 362
             |...||.:  |..::.||...:....|:.....|.|.:: ....|...:|..|  .:......:
pombe   254 IEVTKELNE--EQLDALRKKDKDTAASVLAELFGSENTEEIDTVSKTSGVLELD--NDSTNNFQK 314

  Fly   363 QKQPKEEEEKKEETSSTKAKTADAGNSQASAVSKTAFYIVTDTLRDSLNTRGEGFSLLDMFG--- 424
            :...:::..:|||:.............:.:||      :..|.|::..::..:..|...:||
pombe   315 EGLDEQDNLQKEESVHIDVPAEFEAFDERTAV------VNVDNLKEMFSSNAQDTSKFSLFGNEN 373

  Fly   425 -----SAPEKEVAKRQDQL---EKLGHEKILVGKTSANKLG---LATL-NPFSYDSSDSEDETEV 477
                 |..|.|:..|..:.   |..|...:.:.|.|:...|   :.|| ||.|.....:||.|..
pombe   374 GVGEESEMESEIDDRNYETMEEEADGETPLAIVKASSGTKGWPKMFTLPNPSSLFQPGNEDYTSR 438

  Fly   478 KPKQEQEQEQELEVSKENKAQPAKKSGQKRNKNKLE 513
            :..:....|..|.::::.|.:  :|...||.:...|
pombe   439 EALESWWSENRLFLTRDYKRK--RKDAVKRQRRAHE 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14230	NP_608349.1	RRM	<3..>115	CDD:223796	26/119 (22%)
CG14230	NP_608349.1	RRM_SF	7..77	CDD:240668	21/79 (27%)
SPBP16F5.06	NP_595780.1	RRM_NOL8	6..84	CDD:240672	22/84 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005063
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105160
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1972
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830