DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14230 and K07F5.14

DIOPT Version :9

Sequence 1:	NP_608349.1	Gene:	CG14230 / 32984	FlyBaseID:	FBgn0031062	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_501773.1	Gene:	K07F5.14 / 177837	WormBaseID:	WBGene00010638	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	440	Identity:	110/440 - (25%)
Similarity:	192/440 - (43%)	Gaps:	89/440 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 EQKRKESLNK-----MRQGHQQKKSAIQQ-ALSVISVEGSQAKRIKFSDA-----EEEEASKPV- 242
            ::||::..::     |||..|.::...:| |..:.:|:....|||.|.|:     ::||..|..
Worm     7 DEKRRQRSDEARRAAMRQKIQDQRERDRQIAADIANVDKKTTKRIVFEDSDDGDDQDEETEKTAA 71

  Fly   243 ----QKAKIQKR-DLF----ENDDDEEEEQIVLPQHKGKKGERLVEMQSKQSIDPRFRITSNFV- 297
                :.::..|| .||    |||.||||:..:..:|.|.|||:|:.::|:.:.||||::...|.
Worm    72 NGEKKTSRSSKRPKLFDSEDENDKDEEEDFEIKNRHSGPKGEKLMHLESRFNSDPRFKLDDKFAE 136

  Fly   298 -NEEEEAELEDQPEPEES--ERKWHMNILEQVVGHAI--TSANDKDGKSPKNKKMLRFDPAKEGH 357
             :.:|:..:|...|.:|.  |:..:..:|.:::|.::  ...|..:..:.|.:...||||....|
Worm   137 SDSDEDGNMEQSSEKQEMKLEKDKNRELLSKILGKSVEEKKPNTIESSTLKARPFTRFDPENPEH 201

  Fly   358 QKLMR----QKQPKEEEEKKEETSSTK-AKTADAGNSQASAVSKTAFYIVTDTLRDSLNTRGEGF 417
            .:.|:    .|.|::.::.:|.|:|.: ...:|.|:..::...|.......:...|....:.|.|
Worm   202 LEWMKAFEASKNPQKVKKTEESTNSDEDGNGSDEGDEDSTEKKKEEVVEKDEESGDESFEKAEIF 266

  Fly   418 SLLDMFGSAPEKEVAKRQDQLEKLGHEKILVGKTSANKLGLATLNPFSYDSSDSEDETEVKPKQE 482
            ..:|...||..||   |:|     |.:....|.:..:.:|.      .||....||:.|...|.|
Worm   267 FKMDDAFSAEMKE---RKD-----GDDPSTGGFSFLSMIGR------KYDDEAVEDDGENLKKIE 317

  Fly   483 QEQEQELEVSKENKAQPAKKSGQKRNKNKLE----------SFFI-PRNDPRLKEGAKFFKSTKA 536
            ..|         :||:|   ||   |.:|:|          .||: |.:|.::|..|..|:.|:.
Worm   318 PTQ---------SKAEP---SG---NVDKIEKSLLKVKVSTKFFVDPLSDEKIKSLAANFRRTQT 367

  Fly   537 ---VVD----HAE----------YDQVKNRLKLLITKKIAKAKKSLPSKD 569
               |:|    |.:          .|.||.:.....|....|.|....::|
Worm   368 VEKVIDKWAPHRDAIFKLWKKQRRDAVKKQKDSFFTNGKRKRKADTGNED 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG14230	NP_608349.1	RRM	<3..>115	CDD:223796
CG14230	NP_608349.1	RRM_SF	7..77	CDD:240668
K07F5.14	NP_501773.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005063
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105160
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1972
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760