Protein Alignment CG14232 and TMED8

DIOPT Version :9

• Sequence 1: NP_001245766.1
• Gene: CG14232 / 32983
• FlyBaseID: FBgn0031061
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_001333060.1
• Gene: TMED8 / 283578
• HGNCID: 18633
• Length: 330
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 128/436 - (29%)
• Similarity: 185/436 - (42%)
• Gaps: 135/436 - (30%)

  Fly    66 QAALGPFN---TSR-APALGVLDVIGRDRQQ------------HWQLLGEITREQAMEGFVDLLD 114
            |||.||.:   |:| ..|.||.|..|.:..|            ...||...|..:.
Human     5 QAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEP--------- 60

  Fly   115 TMCSA-FRP-YIEAVRQDRDETLRKELRLMEEKKEARERQENAQQELLEEGYKEELQRRQLQDAL 177
              ||: .|| .:..|.:|..|.|||....:|            .|.|:    |::|........|
Human    61 --CSSPHRPQMVSPVSKDATEDLRKATGPLE------------AQALV----KQDLLPADQAQVL 107

  Fly   178 NKQTYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDKGHQEAEH 242
            |:.:..|...|...|..|:       |..:|.||
Human   108 NESSVVQMAKYQVPQRSGD-------IVMIQSEH------------------------------- 134

  Fly   243 VPGNNNNSSTDLPNAMEGLKLGEVETQQHQQLAEQQDGHVEQTLEGVGQEQHGEEEYDDYVMICP 307
             .|..:..|.||.:|.   .||:     |::::..                          ::.|
Human   135 -TGAIDVLSADLESAD---LLGD-----HRKVSPP--------------------------LMAP 164

  Fly   308 AKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDIGFGIYFEW 372
            ..|||...:::||:::.. :.:..:.:..|:.||:||||:..||.:.||||||.||||||:||:|
Human   165 PCIWTFAKVKEFKSKLGK-EKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDW 228

  Fly   373 AKPVTNEVTVHVSDSDEDEDCVDEDYLSTTE-----DLESGSLSQERGAVNNPTAAPKAPISIIV 432
            ....:.::||.||||.:|||..:|:.....|     |:|.||.|..||....           ::
Human   229 TPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGE-----------VM 282

  Fly   433 PIYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYY 478
            |:|||:.:.:|..|||.|||||:||||||||||:.||||||:.:||
Human   283 PVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYY 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14232	NP_001245766.1	ACBP	33..117	CDD:279259	16/66 (24%)
		GOLD_2	334..478	CDD:290608	71/148 (48%)
TMED8	NP_001333060.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..78		22/83 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	237..272		15/34 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151433
Domainoid	1	1.000	163	1.000	Domainoid score	I3969
eggNOG	1	0.900	-	-		E1_KOG3878
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D321733at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto89482
orthoMCL	1	0.900	-	-		OOG6_105136
Panther	1	1.100	-	-	O	PTHR22973
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.750