Protein Alignment CG14232 and Acbd3

DIOPT Version :10

• Sequence 1: NP_608348.1
• Gene: CG14232 / 32983
• FlyBaseID: FBgn0031061
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_573488.2
• Gene: Acbd3 / 170760
• MGIID: 2181074
• Length: 525
• Species: Mus musculus
• Alignment Length: 506
• Identity: 204/506 - (40%)
• Similarity: 277/506 - (54%)
• Gaps: 52/506 - (10%)

  Fly     1 MASGTSGTSSSETAQSTDMAPSSAEK----WGFPLIELYRLAFTFYKRNSGKAIHLSYEDNLKLI 61
            :.||.||........:.:.|...|.:    |||.|.|||.||..|||...|||.|.:||:.||.:
Mouse    46 LGSGASGQQREPGEAAAEGAAEEARRMEQHWGFGLEELYGLALRFYKIKDGKAFHPTYEEKLKFV 110

  Fly    62 AFKQQAALGPFNTSRAPALGVLDVIGRDRQQHWQLLGEITREQAMEGFVDLLDTMCSAFRPYI-- 124
            |..:|..|||:|...:|.:|..||:|.||::.|..||.:::|.||..||.||:..|.....|:
Mouse   111 ALHKQVLLGPYNPDTSPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNKCCPLLSAYVAS 175

  Fly   125 --------------EAVRQDRDETLRKELRLMEEKKEARE-----RQENAQQELLEEGYKEELQR 170
                          |..|:.|:|..|:.|:..|||::..|     |:|..::.:.||..:.|.|:
Mouse   176 HRIEKEEEEKRRKAEEERRQREEEERERLQKEEEKRKREEEDRLRREEEERRRIEEERLRLEQQK 240

  Fly   171 RQLQDALNKQTYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDK 235
            :|:..|||.||..||:.||.:|:|||.|||.:||.|||.:||.||||||:   |.|...|....:
Mouse   241 QQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLY---QVQLAQQQAALQ 302

  Fly   236 GHQEAEHVPGNNNNSSTDLPNAMEGLKLGEVETQQHQQLAEQQDGHVEQTLEGVGQEQHGEE-EY 299
            ..||..       .:...||.:.:....|..:|......|:....:.|:.||....|:..|. ..
Mouse   303 KQQEVV-------MAGASLPASSKVNTAGASDTLSVNGQAKTHTENSEKVLEPEAAEEALENGPK 360

  Fly   300 DDYVMICPAKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDI 364
            |...:|....:||||.|:.||.::.. |.|.|||:..|:.|||||||:..|..:|||||||||||
Mouse   361 DSLPVIAAPSMWTRPQIKDFKEKIRQ-DADSVITVRRGEVVTVRVPTHEEGSYLFWEFATDSYDI 424

  Fly   365 GFGIYFEWAKPVTNEVTVHVSDSDEDEDCVDEDYLSTTEDLESGSLSQERGAVNNPTAAPKAPIS 429
            |||:||||.......|:||||:|.::|           |:.|.....:|:...|    |.|..:.
Mouse   425 GFGVYFEWTDSPNAAVSVHVSESSDEE-----------EEEEENVTCEEKAKKN----ANKPLLD 474

  Fly   430 IIVPIYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYYER 480
            .|||:|||:|:.|||.|||.|||.||||||||||||:||:|::||||||.|
Mouse   475 EIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14232	NP_608348.1	ACBP	33..113	CDD:459982	37/79 (47%)
		ClpA	<110..>210	CDD:440308	43/120 (36%)
		GPCR_chapero_1	334..478	CDD:480652	75/143 (52%)
Acbd3	NP_573488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	12..68		5/21 (24%)
		ACBP	81..162	CDD:459982	37/80 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..226		12/45 (27%)
		Q domain, Interaction with PI4KB, TBC1D22A and TBC1D22B. /evidence=ECO:0000250|UniProtKB:Q9H3P7	238..305		34/69 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..346		4/26 (15%)
		GOLD_2	394..524	CDD:464028	76/144 (53%)