DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14232 and acbd3

DIOPT Version :9

Sequence 1:	NP_001245766.1	Gene:	CG14232 / 32983	FlyBaseID:	FBgn0031061	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_012818059.2	Gene:	acbd3 / 100124747	XenbaseID:	XB-GENE-958909	Length:	519	Species:	Xenopus tropicalis

Alignment Length:	502	Identity:	213/502 - (42%)
Similarity:	287/502 - (57%)	Gaps:	52/502 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GTSSSETAQSTDMAPSSAEKWGFPLIELYRLAFTFYKRNSGKAIHLSYEDNLKLIAFKQQAALGP 71
            |.|....||:...|.|..::|||.|.|||.||..|:|...|||.|.:||:.|:|:|..:|..|||
Frog    42 GLSLELRAQTEAAALSMEQRWGFSLGELYGLALRFFKEKDGKAFHPTYEEKLRLVALHKQVLLGP 106

  Fly    72 FNTSRAPALGVLDVIGRDRQQHWQLLGEITREQAMEGFVDLLDTMCSAFRPYI----------EA 126
            :|....|.:|..||:|.||::.|..||.:.|::||..||.||:..|..|..|:          |.
Frog   107 YNPDTCPEVGFFDVLGNDRRKEWAALGNMDRQEAMTEFVSLLNRCCHLFSTYVTSHKIEREEQER 171

  Fly   127 VRQDRDETLRKE------LRLMEE--KKEARERQENAQQELL---EEGYKEELQRRQLQDALNKQ 180
            .|::.:|..|||      |:..||  :||..|||...::|.|   :|.::.|.|::|:..|||.|
Frog   172 RRREEEERRRKEEEERERLQREEERRRKEEEERQRREEEERLRAEDERFRMEQQKQQIMAALNSQ 236

  Fly   181 TYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDKGHQEAEHVPG 245
            |..||:.||.:|:|||.|||.:||.|||.:||.||||||:   |.|...|....:..|||.....
Frog   237 TAVQFQQYAAQQYPGNFEQQQILIRQLQEQHYQQYMQQLY---QVQLAQQQAAIQKQQEAAVARS 298

  Fly   246 NNNNSSTDLPNAMEGLKLGE---VETQQHQQL----AEQQDGHVEQTLEGVGQEQHGEEEYDDYV 303
            .:..:|....:::.....||   |..|.|..|    .|.:...:|..||      :|.:.....|
Frog   299 CSPLTSPSKMHSVGAASPGETPSVNGQSHSHLDSNEPEMESDPLEDLLE------NGPKAESAPV 357

  Fly   304 MICPAKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDIGFGI 368
            :..|: :||||.|:.||.::.. |.|.|||:|.|:.|||||||:..|..:|||||||:||||||:
Frog   358 IAAPS-MWTRPQIKDFKEKIRQ-DADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGV 420

  Fly   369 YFEWAKPVTNEVTVHVSDSDEDEDCVDEDYLSTTEDLESGSLSQERGAVNNPTAAPKAPISIIVP 433
            ||||.......|:||||:|.|||:          ||..:.:.:.|..|..|   |.|..:..|||
Frog   421 YFEWTDSPNTAVSVHVSESSEDEE----------EDEGNENPNSEEKAKKN---ANKPQLDEIVP 472

  Fly   434 IYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYYER 480
            :|||:|:.|||.|||.|||.||||||||||||:||:|::||||||.|
Frog   473 VYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14232	NP_001245766.1	ACBP	33..117	CDD:279259	38/83 (46%)
CG14232	NP_001245766.1	GOLD_2	334..478	CDD:290608	78/143 (55%)
acbd3	XP_012818059.2	ACBP	68..153	CDD:395715	38/84 (45%)
acbd3	XP_012818059.2	GOLD_2	386..518	CDD:404736	79/144 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3790
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2138
OMA	1	1.010	-	-		QHG45273
OrthoDB	1	1.010	-	-		D321733at33208
OrthoFinder	1	1.000	-	-		FOG0006065
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22973
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3966
SonicParanoid	1	1.000	-	-		X4360
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.110