DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14231 and pgp1

DIOPT Version :9

Sequence 1:	NP_001245765.1	Gene:	CG14231 / 32982	FlyBaseID:	FBgn0031060	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_588066.1	Gene:	pgp1 / 2539074	PomBaseID:	SPCC1259.10	Length:	412	Species:	Schizosaccharomyces pombe

Alignment Length:	416	Identity:	122/416 - (29%)
Similarity:	182/416 - (43%)	Gaps:	80/416 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHALRNFAGNGIANVFGCGIRRRLSY----VLGIETSCDDTGIAIVDT---------------TG 46
            :..|:.|....|:..|       |||    .|.||||||||.:::|.|               |.
pombe    18 LKVLQQFRCWNISKTF-------LSYRTLTALAIETSCDDTSVSVVRTSDSSSHCQNEIICLNTH 75

  Fly    47 RVIANVLESQQEFHTRYGGIIPPRAQDLHRARIESAYQRCM-EAAQLKPDQLTAIAVTTRPGLPL 110
            |.|:.        :..||||.|......|:..:....||.: :||:........||||..||:..
pombe    76 RTISK--------YEAYGGIHPTIVIHEHQKNLAKVIQRTISDAARSGITDFDLIAVTRGPGMIG 132

  Fly   111 SLLVGVRFARHLARRLQKPLLPVHHMEAHALQARMEHPEQIGYPFLCLLASGGHCQLVVANGPGR 175
            .|.||:..|:.||..||||||.||||:||||..::|  :.|.:|:|.:|.||||..||.:|....
pombe   133 PLAVGLNTAKGLAVGLQKPLLAVHHMQAHALAVQLE--KSIDFPYLNILVSGGHTMLVYSNSLLN 195

  Fly   176 LTLLGQTLDDAPGEAFDKIGRRLRLHILPEYRLWNG---GRAIEHAAQLASDPLAYEF--PLPL- 234
            ..::..|.|.|.|:..||..:.|.:.       |:.   ..|:|..|....:..:|..  |:||
pombe   196 HEIIVTTSDIAVGDYLDKCAKYLGIP-------WDNEMPAAALEQFASPEINSTSYSLKPPIPLN 253

  Fly   235 --AQQRNCNFSFAGIKNNSFRAIRARERAERTPPDGVISNYGDFCAGLLRSVSRHLMHRTQRAIE 297
              .:..:.:|||:|:::.:.|.||      :||.:  :|....|...|..:..:|:..:|
pombe   254 TREKVHSASFSFSGLESYACRIIR------KTPLN--LSEKKFFAYQLQYAAFQHICQKT----- 305

  Fly   298 YCLLPHRQLFGDTPPTLVMSGGVANNDAI---------YANIEHLAAQYGCRSFRPSKRYCSDNG 353
              ||..::|.......||.|||||.|:.:         ....||....  .:...||...||||.
pombe   306 --LLALKRLDLSKVKYLVCSGGVARNELLKKMLNDTLMVLQFEHQPTD--IKLVYPSPDICSDNA 366

  Fly   354 VMIAWHGVEQLLQDKEASTRYDYDSI 379
            .||.:..::.......:|  :|.:.|
pombe   367 AMIGYTAIQMFKAGYTSS--FDVEPI 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14231	NP_001245765.1	T6A_TsaD_YgjD	27..365	CDD:274748	112/370 (30%)
CG14231	NP_001245765.1	Carbam_trans_N	27..>156	CDD:304575	53/144 (37%)
pgp1	NP_588066.1	TsaD	39..403	CDD:223607	115/388 (30%)
pgp1	NP_588066.1	Carbam_trans_N	92..>223	CDD:304575	50/139 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I1663
eggNOG	1	0.900	-	-		E1_COG0533
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I1483
OMA	1	1.010	-	-		QHG62482
OrthoFinder	1	1.000	-	-		FOG0003715
OrthoInspector	1	1.000	-	-		oto100488
orthoMCL	1	0.900	-	-		OOG6_100288
Panther	1	1.100	-	-	LDO	PTHR11735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R915
SonicParanoid	1	1.000	-	-		X2576
TreeFam	1	0.960	-	-
	13	12.860